Kevin Monahan

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Imperial College London

United Kingdom

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The Lynch Syndrome Cancer Prevention Study (‘LynC’ Study)

Open Date: 2020-04-01

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Collaborators (14)

Andrea Sartore-Bianchi

Associate Professor

Università degli Studi di Torino

ITALY

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Philip Quirke

University of Leeds

UNITED KINGDOM

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Miranda Durkie

Deputy head of rare disease

UNITED KINGDOM

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Toni Seppälä

University of Tampere

FINLAND

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Diana M Eccles

University of Southampton

UNITED KINGDOM

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Neil Ryan

University of Bristol

UNITED KINGDOM

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Ann-Sofie Backman

Karolinska Institutet

SWEDEN

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Aysel Ahadova

GERMANY

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Anna Henriikka Lepistö

University of Helsinki

FINLAND

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Vincent Heuveline

Heidelberg University

GERMANY

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Marco Vitellaro

Fondazione IRCCS Istituto Nazionale dei Tumori

ITALY

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Helen Hanson

University of Exeter

UNITED KINGDOM

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Adam Brentnall

Queen Mary University of London

UNITED KINGDOM

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Annika Lindblom

Karolinska Institutet

SWEDEN

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Kevin Monahan

Research Interests

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Recent Grants

Articles (20)

Where do non-invasive colorectal cancer tools ‘FIT’ alongside colonoscopy in the surveillance of high-risk patients?

Carrier testing for partners ofMUTYHvariant carriers: UK Cancer Genetics Group recommendations

Incidences of colorectal adenomas and cancers under colonoscopy surveillance suggest an accelerated “Big Bang” pathway to CRC in three of the four Lynch syndromes

Ovarian cancer: identifying and managing familial and genetic risk-summary of new NICE guidance.

Challenges in developing and implementing international best practice guidance for intermediate-risk variants in cancer susceptibility genes:<i>APC</i>c.3920T&gt;A p.(Ile1307Lys) as an exemplar

The diagnostic yield of colonoscopic surveillance following resection of early age onset colorectal cancer

Mechanisms and management of loss of response to anti-TNF therapy for patients with Crohn's disease: 3-year data from the prospective, multicentre PANTS cohort study.

In vitro study of radiosensitivity in colorectal cancer cell lines associated with Lynch syndrome

Extent of investigation and management of cases of ‘unexplained’ mismatch repair deficiency (u-dMMR): a UK Cancer Genetics Group consensus

Identification of people with Lynch syndrome from those presenting with colorectal cancer in England: baseline analysis of the diagnostic pathway.

Risk-stratified faecal immunochemical testing (FIT) for urgent colonoscopy in Lynch syndrome during the COVID-19 pandemic.

From diagnosis of colorectal cancer to diagnosis of Lynch syndrome: The RM Partners quality improvement project.

Biology of Precancers and Opportunities for Cancer Interception: Lesson from Colorectal Cancer Susceptibility Syndromes

Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database

2022 CGA-IGC Annual Meeting: The collaborative group of the Americas on Inherited Gastrointestinal Cancer November 11–13, 2022

A Focused Clinical Review of Lynch Syndrome

InSiGHT 2022 Abstract Publishing and Best Abstract Awards

Evaluation of a real-time computer-aided polyp detection system during screening colonoscopy: AI-DETECT study

Delphi initiative for early-onset colorectal cancer (DIRECt). International Management Guidelines

Exploring the utility and acceptability of Faecal immunochemical testing (FIT) as a novel intervention for the improvement of colorectal Cancer (CRC) surveillance in individuals with lynch syndrome (FIT for lynch study): a single-arm, prospective, multi-centre, non-randomised study

Collaborators (14)

Andrea Sartore-Bianchi

Philip Quirke

Miranda Durkie

Toni Seppälä

Diana M Eccles

Neil Ryan

Ann-Sofie Backman

Aysel Ahadova

Anna Henriikka Lepistö

Vincent Heuveline

Marco Vitellaro

Helen Hanson

Adam Brentnall

Annika Lindblom

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Challenges in developing and implementing international best practice guidance for intermediate-risk variants in cancer susceptibility genes:<i>APC</i>c.3920T>A p.(Ile1307Lys) as an exemplar