Kim Andrews

The modification in the structures of these compounds offers high degree of diversity and provides a gateway for the production and development of new therapeutic agents with enhanced potency and lesser toxicity. The present study involves the design and synthesis of some newer derivatives of isoxazole, pyrazole and thiadiazole by incorporating the phenoxyl/phenylamino linkage. The chemical structures of the synthesized compounds was confirmed by 1H NMR, 13C NMR, IR, UV-Vis spectroscopy, mass spectrometry and elemental analysis