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Kimberley Bruce

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Associate Professor

University of Colorado Anschutz Medical Campus

United States

Research Interests

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Recent Grants

Grant: Close

Does GLUT5-mediated Fructose Metabolism drive Microglial Dysfunction in Aging and Alzheimer's Disease?

Open Date: 2024-09-30

Close Date: 2026-08-31

Grant: Open

Targeting Microglial Lipoprotein Lipase in Alzheimer's disease

Open Date: 2022-09-15

Close Date: 2027-05-31

Grant: Close

Developing Fluorescence Lifetime Imaging Microscopy (FLIM) as a novel method to measure microglial metabolism in situ

Open Date: 2020-08-15

Close Date: 2022-08-14

Grant: Close

Microglial Lipoprotein Lipase; a novel therapeutic Target for Alzheimer's disease

Open Date: 2019-01-15

Close Date: 2021-11-30

Articles (13)

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2025

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2025

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2024

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2024

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2023

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University of Kentucky

UNITED STATES

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Kimberley Bruce

Research Interests

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Recent Grants

Articles (13)

Are <i>CELSR2 </i>Intronic Variants Genetic Determinants of Energy Balance?

Do microglia metabolize fructose in Alzheimer's disease?

GPR182 is a lipoprotein receptor for dietary fat absorption

Lipid and lipoprotein metabolism in microglia: Alzheimer's disease mechanisms and interventions

Obesity-Induced MASLD Is Reversed by Capsaicin via Hepatic TRPV1 Activation

Proteomic analysis of cerebrospinal fluid from females with multiple sclerosis highlights elevated microglial function and impaired neurogenesis

Synergistic reduction in interfacial flexibility of TREM2<SUP>R47H</SUP> and ApoE4 may underlie AD pathology

The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids

Altered metabolism and DAM-signatures in female brains and microglia with aging.

Fatty acid sensing in the brain: The role of glial-neuronal metabolic crosstalk and horizontal lipid flux

Human cerebrospinal fluid contains diverse lipoprotein subspecies enriched in proteins implicated in central nervous system health

Can DNA Methylation Predict the Lipid Response to Dietary Intervention? There's a Fat Chance

Emerging Alzheimer's disease therapeutics: promising insights from lipid metabolism and microglia-focused interventions

Collaborators (6)

Donna Wilcock

Snigdha Sarkar

Christy Niemeyer

Jason McDermott

Robert H Eckel

Linda Van Eldik

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