Kiran Mahajan

Assistant Professor of Surgery

Washington University in St. Louis

United States

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About

Dr. Kiran Mahajan is an Assistant Professor of Surgery at Washington University in Saint Louis, USA. His research primarily focuses on the epigenetic mechanisms involved in prostate cancer, with recent articles exploring topics such as the role of SHP2 in androgen receptor homeostasis and the impact of HOXB13 on tumor-immune dynamics. Dr. Mahajan is also involved in investigating immunotherapy strategies for prostate cancer and the epigenetic regulation of cancer cell cycles.

Articles (13)

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2020

Collaborators (10)

Bo Zhang

Associate Professor

Washington University in St. Louis

UNITED STATES

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Myung Sik Jeon

Washington University in St. Louis

UNITED STATES

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Dengfeng Cao

Washington University School of Medicine

UNITED STATES

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Charles Nottingham

Assistant Professor

Washington University Physicians

UNITED STATES

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Ian Hagemann

Associate Professor

Washington University in Saint Louis School of Medicine

UNITED STATES

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Tiandao Li

Washington University in St. Louis

UNITED STATES

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Nupam P. Mahajan

Washington University in St. Louis

UNITED STATES

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Joseph E Ippolito

Washington University School of Medicine

UNITED STATES

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Eric Kim

Associate Professor of Surgery

Washington University in Saint Louis School of Medicine

UNITED STATES

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jingqin luo

Associate Professor

Washington University in Saint Louis School of Medicine

UNITED STATES

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Kiran Mahajan

Research Interests

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Articles (13)

SHP2 as a primordial epigenetic enzyme expunges histone H3 pTyr-54 to amend androgen receptor homeostasis

Symptomatic Benign Prostatic Hyperplasia with Suppressed Epigenetic Regulator HOXB13 Shows a Lower Incidence of Prostate Cancer Development

Prostate-Specific Membrane Antigen–Targeted Imaging and Its Correlation with HOXB13 Expression

Amino Terminal Acetylation of HOXB13 Regulates the DNA Damage Response in Prostate Cancer

Epigenetic underpinnings of tumor-immune dynamics in prostate cancer immune suppression

Epigenetic reprogramming of cell cycle genes by ACK1 promotes breast cancer resistance to CDK4/6 inhibitor

Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer

Prostate cancer immunotherapy: Improving clinical outcomes with a multi-pronged approach.

Loss of Long Noncoding RNA NXTAR in Prostate Cancer Augments Androgen Receptor Expression and Enzalutamide Resistance

Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting

Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance.

Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer.

ACK1-AR and AR-HOXB13 signaling axes: epigenetic regulation of lethal prostate cancers.

Collaborators (10)

Bo Zhang

Myung Sik Jeon

Dengfeng Cao

Charles Nottingham

Ian Hagemann

Tiandao Li

Nupam P. Mahajan

Joseph E Ippolito

Eric Kim

jingqin luo

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