Kiran Sapkota

Assistant Professor

University of Nebraska Medical Center

United States

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Dr. Kiran Sapkota is an Assistant Professor at the University of Nebraska Medical Center in the United States. His research focuses on NMDA receptor functions and their implications in schizophrenia, as evidenced by his recent articles exploring receptor dysregulation, pharmacological characterization of novel modulators, and cognitive behavioral restoration through GSK3β inhibition. He is dedicated to advancing the understanding of neuropharmacology and cognitive deficits related to inflammation and apoptosis in rodent models.

Articles (5)

Year:

2022

Year:

2021

Year:

2020

Year:

2020

Year:

2020

Collaborators (1)

Arturas Volianskis

Senior Lecturer in Neuroscience

Cardiff University

UNITED KINGDOM

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Kiran Sapkota

Research Interests

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Articles (5)

5-HT2A receptor dysregulation in a schizophrenia relevant mouse model of NMDA receptor hypofunction.

Pharmacological characterization of a novel negative allosteric modulator of NMDA receptors, UBP792

Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors

GSK3β inhibition restores cortical gamma oscillation and cognitive behavior in a mouse model of NMDA receptor hypofunction relevant to schizophrenia

Pananx notoginseng saponins attenuate CCL2-induced cognitive deficits in rats via anti-inflammation and anti-apoptosis effects that involve suppressing over-activation of NMDA receptors

Collaborators (1)

Arturas Volianskis

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