Konrad A. Szychowski

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Poland

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Pozyskanie substancji bioaktywnych z Inonotus obliquus w formie możliwej do zastosowania we wzbogacaniu żywności

Open Date: 2022-02-01

Close Date: 2022-07-01

Grant: Close

Ocena wykorzystania nanocząstek srebra w terapii przeciwko komórkom nowotworowym mózgu in vitro

Open Date: 2022-01-01

Close Date: 2023-01-01

Grant: Close

Peptyd elastynopochodny VGVAPG jako transporter leków cytostatycznych do komórek nowotworowych

Open Date: 2021-02-01

Close Date: 2021-07-01

Grant: Close

Mechanizm działania triklosanu w neuronach kory mózgowej myszy

Open Date: 2015-01-01

Close Date: 2017-01-01

Articles (29)

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Collaborators (9)

Bartosz Skóra

POLAND

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Kamila Rybczyńska-Tkaczyk

University of Life Sciences in Lublin

POLAND

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Ireneusz Sowa

prof

Medical University of Lublin

POLAND

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Roman Lesyk

Professor

University of Information Technology and Management in Rzeszow

POLAND

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Tadeusz Pomianek

University of Information Technology and Management in Rzeszow

POLAND

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Anna K. Wójtowicz

professor

University of Agriculture

POLAND

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Lucjusz Zaprutko

Poznan University of Medical Sciences

POLAND

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Oliwia Koszła

Medical University of Lublin

POLAND

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Dmytro Khyluk

Medical University of Lublin

POLAND

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Konrad A. Szychowski

Research Interests

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Recent Grants

Articles (29)

Oxidative stress-driven disease-associated microglia (DAM)-like polarization in human microglia (HMC3) cells exposed to small-size silver nanoparticles in a transwell co-culture system with neurons (cholinergic differentiated SH-SY5Y) cells in vitro

Current State of Knowledge on Amiodarone (AMD)-Induced Reactive Oxygen Species (ROS) Production in In Vitro and In Vivo Models

Impact of Hericium erinaceus and Ganoderma lucidum metabolites on AhR activation in neuronal HT-22 cells

Aryl Hydrocarbon Receptor (AhR)–Independent Amiodarone (AMD) Toxicity in HepG2 Cell Line

Proteostasis and autophagy disruption by the aging-related VGVAPG hexapeptide - preliminary insights into a potential novel elastin-induced neurodegeneration pathway in an in vitro human cellular neuron model

Tris(2-chloroisopropyl) phosphate (TCPP) decreases CYP1A1, CYP1A2, and CYP1B1/CYP2B expression and activities through potential interactions between AhR and NRF2 pathways in the HepG2 cell line

Carboxychalcones Based on Terephthalaldehydic Acid as Potential Neuroprotective Agents. Synthesis, Computational Study and Biological Evaluation

Biotransformation of Ganoderma lucidum and Hericium erinaceus for ex vivo gut-brain axis modulation and mood-related outcomes in humans: CREB/BDNF signaling and microbiota-driven synergies

Comparison of the Cytotoxic Mechanisms of Different Garlic (<i>Allium sativum</i> L.) Cultivars with the Crucial Involvement of Peroxisome Proliferator-Activated Receptor Gamma

Elastin-derived peptides (EDPs) affect gene and protein expression in human mesenchymal stem cells (hMSCs) – preliminary study

Engagement of specific intracellular pathways in the inflammation-based reprotoxicity effect of small-size silver nanoparticles on spermatogonia and spermatocytes in vitro cell models

Anticancer Properties of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Potential Agonists 4-Thiazolidinone-Pyrazoline Hybrids Les-4368 and Les-4370 in Colorectal Adenocarcinoma Cells In Vitro

Elastin-derived peptides (EDPs) as a potential pro-malignancy factor in human leukemia cell lines

Role of Ciminalum-4-thiazolidinone Hybrids in Molecular NF-κB Dependent Pathways

Current state of knowledge of triclosan (TCS)-dependent reactive oxygen species (ROS) production

Role of 4-Thiazolidinone–Pyrazoline/Indoline Hybrids Les-4369 and Les-3467 in BJ and A549 Cell Lines

Comparison of the Antioxidant and Cytoprotective Properties of Extracts from Different Cultivars of Cornus mas L.

Curcuminoid Chalcones: Synthesis and Biological Activity against the Human Colon Carcinoma (Caco-2) Cell Line

Involvement of peroxisome proliferator‐activated receptor gamma (PPARγ) and autophagic pathways in the mechanism of action of the tris(2,3‐dibromopropyl) isocyanurate (TDBP‐TAZTO or TBC) flame retardant in the lung adenocarcinoma (A549) cells in vitro

Pyrrolidinedione-thiazolidinone hybrid molecules with potent cytotoxic effect in squamous cell carcinoma SCC-15 cells

Suppression of sonic hedgehog pathway-based proliferation in glioblastoma cells by small-size silver nanoparticles in vitro

Disruption of neurosteroid synthesis and release by tris(2,3‐dibromopropyl)isocyanurate in primary mouse cortical astrocytes in vitro

Tris(2,3-dibromopropyl)Isocyanurate has an Effect on Inflammation Markers in Mouse Primary Astrocytes In vitro

Toxicity of bisphenol A (BPA) and its derivatives in divers biological models with the assessment of molecular mechanisms of toxicity

Reprotoxic Effect of Tris(2,3-Dibromopropyl) Isocyanurate (TBC) on Spermatogenic Cells In Vitro

Involvement of the aryl hydrocarbon receptor (AhR) in the mechanism of action of elastin-derived peptide (VGVAPG) and its impact on neurosteroidogenesis

Elastin-Derived Peptides in the Central Nervous System: Friend or Foe

Comprehensive review of the impact of tris(2,3-dibromopropyl) isocyanurate (TBC or TDBP-TAZTO) on living organisms and the environment

Calcium channel antagonists interfere with the mechanism of action of elastin-derived peptide VGVAPG in mouse cortical astrocytes in vitro

Collaborators (9)

Bartosz Skóra

Kamila Rybczyńska-Tkaczyk

Ireneusz Sowa

Roman Lesyk

Tadeusz Pomianek

Anna K. Wójtowicz

Lucjusz Zaprutko

Oliwia Koszła

Dmytro Khyluk

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