Kosuke Nakashima

Assistant Professor

Tokyo University of Pharmacy and Life Sciences

Japan

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About

Professor Kosuke Nakashima is an Assistant Professor at Tokyo University of Pharmacy and Life Sciences in Japan. His research focuses on organic synthesis, particularly in the development of chiral compounds and organocatalysis, as evidenced by his recent publications on topics such as vicinal bisphosphine derivatives and the synthesis of indoles. He is actively engaged in exploring the stability of Z-isomers and the applications of organocatalysts in asymmetric reactions.

Articles (20)

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2025

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2022

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2022

Collaborators (6)

Shin-ichi Hirashima

Associate Professor

Tokyo University of Pharmacy and Life Sciences

JAPAN

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Martin Vala

Brno University of Technology

CZECH REPUBLIC

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Jozef Krajcovic

Brno University of Technology

CZECH REPUBLIC

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Liudmil Antonov

BULGARIA

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Akihiro Yoshida

Professor (Associate)

Josai University

JAPAN

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Hiroshi Akutsu

Assistant Professor

Josai University

JAPAN

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Kosuke Nakashima

Research Interests

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About

Articles (20)

Asymmetric ε-regioselective conjugate addition of 2-furfuryl ketones to nitroalkenes using a thiourea organocatalyst

Visible Light Switching of Ortho-Functionalized Azo Phthalimides with Tunable Z-Isomer Stability

Intramolecular through-space conjugation of chiral C2-spirooxindole

Synthesizing Chiral Vicinal Bisphosphine Derivatives through Hydrophosphinylation and Asymmetric Protonation of Secondary Phosphine Sulfides with Vinylphosphine Oxides

Regioselective One-Pot Synthesis of Vicinal Bisphosphine Derivatives from Nitroalkenes by Hydrophosphinylation/Elimination/Hydrophosphinylation

Rearrangement of C2-Spirooxindoles: Conversion to the 2-Hydroxyhemi-Indigo and Chromenoindole

Organocatalyzed Synthesis of γ-Alkenyl Butenolides via Asymmetric Direct Vinylogous Conjugate Addition–Elimination of Substituted Furanone Derivatives to β-Phenylsulfonylenones

Organocatalyzed Asymmetric Cascade Michael/Michael Reaction of α‐Alkylidene Succinimides with a 2‐(Trifluoromethylmethylene)indane‐1,3‐dione

Synthesis of 2-Substituted Indoles <i>via</i> Migration Reaction of 3-Substituted Indoles with Triflic Acid

Vicinal All‐Carbon Quaternary Stereocenter Construction with Trifluoromethyl Groups via Organocatalytic Asymmetric Cascade Michael/Michael Reaction

Asymmetric Direct Vinylogous Conjugate Addition of α,β-Unsaturated γ-Butyrolactam to Acyl Acrylonitriles using Organocatalysts

Highly efficient, asymmetric, and organocatalyst-based Henry reactions between α,β-unsaturated trifluoromethyl ketone and nitromethane

Control over rotary motion and multicolour switching in 3-hydroxyphthalimide fluorophores: An interplay between AIE and ESIPT

Asymmetric Henry Reaction of Trifluoromethyl Enones with Nitromethane Using a N,N ‐Dibenzyl Diaminomethylenemalononitrile Organocatalyst

Asymmetric Direct Vinylogous Conjugate Addition of Substituted Furanone Derivatives to (E)- and (Z)-Benzoyl Acrylonitriles Using Organocatalysts

Asymmetric Friedel−Crafts Alkylation of Indoles with α,β-unsaturated Trifluoromethyl Ketones Using a Squaramide Organocatalyst

Asymmetric conjugate addition–cyclization of cyclohexane-1,2-dione with alkylidenemalononitriles using diaminomethylenemalononitrile organocatalyst

Organocatalytic one-pot asymmetric synthesis of 6-trifluoromethyl-substituted 7,8-dihydrochromen-6-ol

Solvent-Triggered Long-Range Proton Transport in 7-Hydroxyquinoline Using a Sulfonamide Transporter Group

Synthesis of Chiral α-Substituted β-Aminophosphine Derivatives through Asymmetric Hydrophosphinylation Utilizing Secondary Phosphine Sulfides

Collaborators (6)

Shin-ichi Hirashima

Martin Vala

Jozef Krajcovic

Liudmil Antonov

Akihiro Yoshida

Hiroshi Akutsu

Make your next move.

Kosuke Nakashima

Research Interests

Explore related searches

Contact this professor

About

Articles (20)

Asymmetric ε-regioselective conjugate addition of 2-furfuryl ketones to nitroalkenes using a thiourea organocatalyst

Visible Light Switching of Ortho-Functionalized Azo Phthalimides with Tunable Z-Isomer Stability

Intramolecular through-space conjugation of chiral C2-spirooxindole

Synthesizing Chiral Vicinal Bisphosphine Derivatives through Hydrophosphinylation and Asymmetric Protonation of Secondary Phosphine Sulfides with Vinylphosphine Oxides

Regioselective One-Pot Synthesis of Vicinal Bisphosphine Derivatives from Nitroalkenes by Hydrophosphinylation/Elimination/Hydrophosphinylation

Rearrangement of C2-Spirooxindoles: Conversion to the 2-Hydroxyhemi-Indigo and Chromenoindole

Organocatalyzed Synthesis of γ-Alkenyl Butenolides via Asymmetric Direct Vinylogous Conjugate Addition–Elimination of Substituted Furanone Derivatives to β-Phenylsulfonylenones

Organocatalyzed Asymmetric Cascade Michael/Michael Reaction of α‐Alkylidene Succinimides with a 2‐(Trifluoromethylmethylene)indane‐1,3‐dione

Synthesis of 2-Substituted Indoles &lt;i&gt;via&lt;/i&gt; Migration Reaction of 3-Substituted Indoles with Triflic Acid

Vicinal All‐Carbon Quaternary Stereocenter Construction with Trifluoromethyl Groups via Organocatalytic Asymmetric Cascade Michael/Michael Reaction

Asymmetric Direct Vinylogous Conjugate Addition of α,β-Unsaturated γ-Butyrolactam to Acyl Acrylonitriles using Organocatalysts

Highly efficient, asymmetric, and organocatalyst-based Henry reactions between α,β-unsaturated trifluoromethyl ketone and nitromethane

Control over rotary motion and multicolour switching in 3-hydroxyphthalimide fluorophores: An interplay between AIE and ESIPT

Asymmetric Henry Reaction of Trifluoromethyl Enones with Nitromethane Using a N,N ‐Dibenzyl Diaminomethylenemalononitrile Organocatalyst

Asymmetric Direct Vinylogous Conjugate Addition of Substituted Furanone Derivatives to (E)- and (Z)-Benzoyl Acrylonitriles Using Organocatalysts

Asymmetric Friedel−Crafts Alkylation of Indoles with α,β-unsaturated Trifluoromethyl Ketones Using a Squaramide Organocatalyst

Asymmetric conjugate addition–cyclization of cyclohexane-1,2-dione with alkylidenemalononitriles using diaminomethylenemalononitrile organocatalyst

Organocatalytic one-pot asymmetric synthesis of 6-trifluoromethyl-substituted 7,8-dihydrochromen-6-ol

Solvent-Triggered Long-Range Proton Transport in 7-Hydroxyquinoline Using a Sulfonamide Transporter Group

Synthesis of Chiral α-Substituted β-Aminophosphine Derivatives through Asymmetric Hydrophosphinylation Utilizing Secondary Phosphine Sulfides

Collaborators (6)

Shin-ichi Hirashima

Martin Vala

Jozef Krajcovic

Liudmil Antonov

Akihiro Yoshida

Hiroshi Akutsu

Make your next move.

Synthesis of 2-Substituted Indoles <i>via</i> Migration Reaction of 3-Substituted Indoles with Triflic Acid