KRISHNE GOWDA

Associate Professor

Penn State Health Milton S Hershey Medical Center

United States

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Dr. Krishne Gowda is an Associate Professor at Penn State Health Milton S Hershey Medical Center in the United States. His research expertise encompasses cancer biology, focusing on areas such as telomerase dysfunction in melanoma, tumor heterogeneity, and the pharmacological targeting of drug-tolerant cancer cells. He has contributed significantly to understanding the interactions between environmental carcinogens and genetic factors, as well as exploring novel therapeutic agents for inflammatory disorders.

Articles (18)

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2025

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2020

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2020

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Harvard University

UNITED STATES

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KRISHNE GOWDA

Research Interests

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Articles (18)

Managing telomerase and telomere dysfunction in acral melanoma

Tumor Heterogeneity Shapes Survival Dynamics in Drug-Treated Cells, Revealing Size-Drifting Subpopulations

Identification of Novel Isatin Derivative Bearing a Nitrofuran Moiety as Potent Multi-Isoform Aldehyde Dehydrogenase Inhibitor

Pharmacological agents targeting drug-tolerant persister cells in cancer.

Gender Difference in DNA Damage Induced by the Environmental Carcinogen Dibenzo[def,p]chrysene Individually and in Combination with Mouse Papillomavirus Infection in the Mouse Oral Cavity

Induction of AHR Signaling in Response to the Indolimine Class of Microbial Stress Metabolites

Complex chemical signals dictate Ah receptor activation through the gut–lung axis

Contribution of Circulating Host and Microbial Tryptophan Metabolites Toward Ah Receptor Activation.

Delivery of Therapeutic miR-148b Mimic via Poly(β Amino Ester) Polyplexes for Post-transcriptional Gene Regulation and Apoptosis of A549 Cells

Black Raspberry Extract Enhances Glutathione Conjugation of the Fjord-Region Diol Epoxide Derived from the Tobacco Carcinogen Dibenzo[def,p]chrysene in Human Oral Cells

Detection of DNA Adducts Derived from the Tobacco Carcinogens, Benzo[a]pyrene and Dibenzo[def,p]chrysene in Human Oral Buccal Cells.

Lead optimization of aryl hydrocarbon receptor ligands for treatment of inflammatory skin disorders.

Lipoxygenase catalyzed metabolites derived from docosahexaenoic acid are promising antitumor agents against breast cancer.

The environmental pollutant and tobacco smoke constituent dibenzo[def,p]chrysene is a co-factor for malignant progression of mouse oral papillomavirus infections

IKAROS and CK2 regulate expression of BCL-XL and chemosensitivity inhigh-risk B-cell acute lymphoblastic leukemia.

Intestinal microbiota-derived tryptophan metabolites are predictive of Ah receptor activity.

Black Raspberry Inhibits Oral Tumors in Mice Treated with the Tobacco Smoke Constituent Dibenzo(def,p)chrysene Via Genetic and Epigenetic Alterations

Development of a Novel Multi-Isoform ALDH Inhibitor Effective as an Antimelanoma Agent

Collaborators (7)

Gavin P. Robertson

Kimberly Payne

Arun Sharma

Imhoi Koo

Daniel Hayes

Andrew Patterson

FANGCONG DONG

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