Kristopher Bosse

Assistant Professor

Children's Hospital of Philadelphia

United States

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Dr. Kristopher Bosse is an Assistant Professor at The Children's Hospital of Philadelphia, USA. His research primarily focuses on neuroblastoma, particularly in the areas of immunotherapy and targeted therapies. Recent publications highlight his work on immunotherapeutic targets, CAR T-cell applications, and the genetic aspects influencing patient outcomes in neuroblastoma.

Articles (10)

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

Collaborators (4)

Samuel Aparicio

Head

CANADA

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Sonia Kung

CANADA

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Gurdeep Singh

Assistant Professor

University of New Mexico

UNITED STATES

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Poul H. Sorensen

The University of British Columbia

CANADA

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Kristopher Bosse

Research Interests

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Articles (10)

A proteogenomic surfaceome study identifies DLK1 as an immunotherapeutic target in neuroblastoma.

CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma.

Targeting GPC2 on Intraocular and CNS Metastatic Retinoblastomas with Local and Systemic Delivery of CAR T Cells.

BARD1 germline variants induce haploinsufficiency and DNA repair defects in neuroblastoma.

Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival.

A MYCN-independent mechanism mediating secretome reprogramming and metastasis in <i>MYCN</i>-amplified neuroblastoma.

Targeting of intracellular oncoproteins with peptide-centric CARs.

GPC2 antibody-drug conjugate reprograms the neuroblastoma immune milieu to enhance macrophage-driven therapies.

Serial Profiling of Circulating Tumor DNA Identifies Dynamic Evolution of Clinically Actionable Genomic Alterations in High-Risk Neuroblastoma.

Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors.

Collaborators (4)

Samuel Aparicio

Sonia Kung

Gurdeep Singh

Poul H. Sorensen

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