Kuangwen Hsieh

Assistant Research Professor

Johns Hopkins University

United States

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About

Kuangwen Hsieh is an Assistant Research Professor at Johns Hopkins University in the United States. His research focuses on innovative diagnostics and biosensing technologies, particularly in the areas of pathogen detection, cancer biomarker analysis, and HIV quantification. Recent publications highlight advancements in CRISPR applications and digital profiling methodologies, underscoring his contributions to the fields of molecular biology and clinical diagnostics.

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2020

Collaborators (6)

Tza-Huei Wang

Johns Hopkins University

UNITED STATES

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Tine Curk

Northwestern University

UNITED STATES

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Pak Kin Wong

Pennsylvania State University

UNITED STATES

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Joseph Liao

Stanford University

UNITED STATES

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Thomas Pisanic

Associate Research Professor

Johns Hopkins University School of Medicine

UNITED STATES

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Efrosini Kokkoli

Professor

Johns Hopkins University

UNITED STATES

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Kuangwen Hsieh

Research Interests

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About

Articles (25)

Cross-kingdom pathogen detection via duplex universal PCR and high-resolution melt

Improving bacteria identification from digital melt assay via oligonucleotide-based temperature calibration

Single-Particle Spectroscopic Chromatography Reveals Heterogeneous RNA Loading and Size Correlations in Lipid Nanoparticles

Rapid and portable quantification of HIV RNA via a smartphone-enabled digital CRISPR device and deep learning

Multiplex digital profiling of DNA methylation heterogeneity for sensitive and cost-effective cancer detection in low-volume liquid biopsies

Digitized Kinetic Analysis Enhances Genotyping Capacity of CRISPR-Based Biosensing

Cancer Methylation Biomarker Detection in an Automated, Portable, Multichannel Magnetofluidic Platform

Harnessing Variabilities in Digital Melt Curves for Accurate Identification of Bacteria

Single-cell pathogen diagnostics for combating antibiotic resistance

Elucidating the Role of CRISPR/Cas in Single-Step Isothermal Nucleic Acid Amplification Testing Assays

Combating Antimicrobial Resistance via Single-Cell Diagnostic Technologies Powered by Droplet Microfluidics

Magnetofluidic immuno-PCR for point-of-care COVID-19 serological testing

Payload distribution and capacity of mRNA lipid nanoparticles

Sensitive and Quantitative Point-of-Care HIV Viral Load Quantification from Blood Using a Power-Free Plasma Separation and Portable Magnetofluidic Polymerase Chain Reaction Instrument

Emerging Multiplex Nucleic Acid Diagnostic Tests for Combating COVID-19

Highly Sensitive Serum Protein Analysis Using Magnetic Bead-Based Proximity Extension Assay

Ratiometric PCR in a Portable Sample-to-Result Device for Broad-Based Pathogen Identification

Point-of-care CRISPR-Cas-assisted SARS-CoV-2 detection in an automated and portable droplet magnetofluidic device

Digital CRISPR/Cas‐Assisted Assay for Rapid and Sensitive Detection of SARS‐CoV‐2

Toward Decentralizing Antibiotic Susceptibility Testing via Ready-to-Use Microwell Array and Resazurin-Aided Colorimetric Readout

Digital electrical impedance analysis for single bacterium sensing and antimicrobial susceptibility testing

Droplet-Based Single-Cell Measurements of 16S rRNA Enable Integrated Bacteria Identification and Pheno-Molecular Antimicrobial Susceptibility Testing from Clinical Samples in 30 min

Facile syringe filter-enabled bacteria separation, enrichment, and buffer exchange for clinical isolation-free digital detection and characterization of bacterial pathogens in urine

Portable Magnetofluidic Device for Point-of-Need Detection of African Swine Fever

Facile Coupling of Droplet Magnetofluidic-Enabled Automated Sample Preparation for Digital Nucleic Acid Amplification Testing and Analysis

Collaborators (6)

Tza-Huei Wang

Tine Curk

Pak Kin Wong

Joseph Liao

Thomas Pisanic

Efrosini Kokkoli

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