Laura Orsatti

Head of PK/PD Bioanalytics

IRBM Science Park

Italy

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Laura Orsatti is the Head of PK/PD Bioanalytics at IRBM Science Park in Italy. Her research encompasses a variety of areas, including peptide bioanalytics, metabolomics, and methodologies related to the study of therapeutic peptides in diseases such as Huntington's and cardiovascular conditions. Recent publications highlight her work on the optimization of peptide leads and imaging techniques for disease biomarkers.

Articles (10)

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2025

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2023

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2022

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2021

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (3)

Vincenzo Summa

University of Naples Federico II

ITALY

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DANIEL OSCAR CICERO

Associate Professor

Università degli Studi di Roma La Sapienza

ITALY

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Peter Johnson

Head of Medicinal Chemistry

Econick

UNITED KINGDOM

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Laura Orsatti

Research Interests

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Articles (10)

Optimization of Single Relaxin B-Chain Peptide Leads to the Identification of R2R01, a Potent, Long-Acting RXFP1 Agonist for Cardiovascular and Renal Diseases

The Urine Metabolome of R6/2 and zQ175DN Huntington’s Disease Mouse Models

Oligomerization, albumin binding and catabolism of therapeutic peptides in the subcutaneous compartment: An investigation on lipidated GLP-1 analogs

Personalized Metabolic Profile by Synergic Use of NMR and HRMS

Kynurenine pathway activation and deviation to anthranilic and kynurenic acid in fibrosing chronic graft-versus-host disease

[<sup>11</sup>C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins

Turnover rate of coenzyme A in mouse brain and liver

Identification of Potent and Long-Acting Single-Chain Peptide Mimetics of Human Relaxin-2 for Cardiovascular Diseases

Comparison of different protein precipitation and solid‐phase extraction protocols for the study of the catabolism of peptide drugs by LC‐HRMS

Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand

Collaborators (3)

Vincenzo Summa

DANIEL OSCAR CICERO

Peter Johnson

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