Lauren Porter

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National Institutes of Health

United States

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Rational design of protein fold switches by sequence transplantation

Open Date: 2014-01-20

Close Date: 2016-01-19

Articles (10)

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2023

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2023

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2023

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2021

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Liskin Swint‐Kruse

UNITED STATES

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Lauren Porter

Research Interests

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Recent Grants

Articles (10)

Evolutionary selection of proteins with two folds

Fluid protein fold space and its implications

Identification of a covert evolutionary pathway between two protein folds

Distinguishing features of fold‐switching proteins

Many dissimilar NusG protein domains switch between α-helix and β-sheet folds

AlphaFold2 fails to predict protein fold switching

A high‐throughput predictive method for sequence‐similar fold switchers

A sequence‐based method for predicting extant fold switchers that undergo α‐helix ↔ β‐strand transitions

Predictable fold switching by the SARS‐CoV‐2 protein ORF9b

Functional and Regulatory Roles of Fold-Switching Proteins

Collaborators (1)

Liskin Swint‐Kruse

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