Laurent Trembleau

University of Aberdeen

United Kingdom

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Articles (12)

Year:

2024

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2024

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2021

Year:

2021

Collaborators (4)

Hai Deng

University of Aberdeen

UNITED KINGDOM

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David Clarke

Senior Lecturer & Chancellor's Research Fellow

University of Edinburgh

UNITED KINGDOM

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Bruce Milne

Honorary Lecturer

University of Aberdeen

UNITED KINGDOM

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Jioji Tabudravu

University of Central Lancashire

UNITED KINGDOM

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Laurent Trembleau

Research Interests

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Articles (12)

Accraspiroketides A-B, Phenylnaphthacenoid-Derived Polyketides with Unprecedented [6+6+6+6]+[5+5] Spiro-Architecture

Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity

Design, Synthesis, and Biological Evaluation of Indole-2-carboxamides as Potential Multi-Target Antiproliferative Agents

Design, synthesis, apoptotic, and antiproliferative effects of 5-chloro-3- (2-methoxyvinyl)-indole-2-carboxamides and pyrido[3,4-b]indol-1-ones as potent EGFRWT/EGFRT790M inhibitors

Discovery of new 5-substituted-indole-2-carboxamides as dual epidermal growth factor receptor (EGFR)/cyclin dependent kinase-2 (CDK2) inhibitors with potent antiproliferative action

Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFRT790M/BRAFV600E Pathways

A ribosomally synthesised and post-translationally modified peptide containing a β-enamino acid and a macrocyclic motif

Synthesis and Biological Evaluation of Indole-2-Carboxamides with Potent Apoptotic Antiproliferative Activity as EGFR/CDK2 Dual Inhibitors

Characterization of a class II ketol-acid reductoisomerase from Mycobacterium tuberculosis

Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities

Discovery of novel oxazole-based macrocycles as anti-coronaviral agents targeting SARS-CoV-2 main protease

Novel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects

Collaborators (4)

Hai Deng

David Clarke

Bruce Milne

Jioji Tabudravu

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