Leandro Sastre

Assistant Professor

Consejo Superior de Investigaciones Cientificas

Spain

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About

Leandro Sastre is an Assistant Professor at the Consejo Superior de Investigaciones Cientificas in Spain. His research areas include the genetic underpinnings of telomere-related conditions, the biology of colorectal cancer stem cells, and novel therapeutic approaches for lung diseases and hematological disorders. Dr. Sastre has contributed significantly to understanding oxidative stress and DNA damage in relation to telomerase components and has been involved in collaborative initiatives for research on rare diseases.

Articles (7)

Year:

2024

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Collaborators (20)

Angel Campos-Barros

Head of the Molecular Endocrinology Division

La Paz University Hospital

SPAIN

Leandro Sastre

Research Interests

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About

Articles (7)

Clinical mutations in the TERT and TERC genes coding for telomerase components induced oxidative stress, DNA damage at telomeres and cell apoptosis besides decreased telomerase activity

CIBERER: Spanish National Network for Research on Rare Diseases: a highly productive collaborative initiative.

Comparison of Colorectal Cancer Stem Cells and Oxaliplatin-Resistant Cells Unveils Functional Similarities

Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of DKC1

GSE4‐loaded nanoparticles a potential therapy for lung fibrosis that enhances pneumocyte growth, reduces apoptosis and DNA damage

Next-generation Sequencing in Bone Marrow Failure Syndromes and Isolated Cytopenias: Experience of the Spanish Network on Bone Marrow Failure Syndromes.

Telomere-Related Gene Mutations and Lung Diseases: Pulmonary Fibrosis, Emphysema and Lung Cancer

Collaborators (20)

Angel Campos-Barros

Guillermo Guenechea

Pilar Rodríguez-Pombo

Elena Martín-Hernández

Francisco Barros

Elena Vallespín

Lucía Martínez-Santamaría

Massimo Bogliolo

Noèlia Fernàndez-Castillo

Joana Fort

Ana Latorre-Pellicer

Raquel Rabionet

Juan Andres Jimenez Estrada

Carlos Santos Ocaña

Beatriz Fernández Varas

Alberto Marina

Saoud Tahsin Swafiri Swafiri

María José Escámez

Mercedes Gil-Campos

Cristina Ugalde

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