Leona Raskova Kafkova

assistant professor

Palacký University, Olomouc

Czech Republic

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Leona Raskova Kafkova is an assistant professor at Palacký University in Olomouc, Czech Republic. Her research focuses on immunology and cancer therapy, as evidenced by her recent publications that explore topics such as antibody elicitation for HIV-1, protein engineering for diagnostics, and the role of interleukin-6 in cancer development. She is actively involved in investigating innovative therapeutics and targeting immune checkpoints in various cancer types.

Articles (11)

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2024

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2024

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2024

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2024

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2024

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2023

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2022

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2022

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2021

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2021

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2021

Collaborators (6)

Michal Křupka

Lékařská Fakulta Univerzita Palackého v Olomouci

CZECH REPUBLIC

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Petr Malý

Head of Research Group

Institute of Biotechnology of the Czech Academy of Sciences

CZECH REPUBLIC

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Hana Petrokova

Czech Academy of Sciences, Institute of Botany

CZECH REPUBLIC

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Milan Raska

University Hospital Olomouc

CZECH REPUBLIC

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Valeria Skopelidou

University Hospital Ostrava

CZECH REPUBLIC

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Marek Sinkora

Head of laboratory

Czech Academy of Sciences, Institute of Microbiology

CZECH REPUBLIC

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Leona Raskova Kafkova

Research Interests

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Articles (11)

NSCLC: from tumorigenesis, immune checkpoint misuse to current and future targeted therapy

Engineering PD-1-targeted small protein variants for in vitro diagnostics and in vivo PET imaging

Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells

Beyond glycan barriers: non-cognate ligands and protein mimicry approaches to elicit broadly neutralizing antibodies for HIV-1

Human IL-22 receptor-targeted small protein antagonist suppress murine DSS-induced colitis

Potential predictors of immunotherapy in small cell lung cancer

IL-6 and its role in IgA nephropathy development

Myomedin replicas of gp120 V3 loop glycan epitopes recognized by PGT121 and PGT126 antibodies as non-cognate antigens for stimulation of HIV-1 broadly neutralizing antibodies

Myomedin scaffold variants targeted to 10E8 HIV-1 broadly neutralizing antibody mimic gp41 epitope and elicit HIV-1 virus-neutralizing sera in mice

Preparation and properties of recombinant Clostridium ramosum IgA proteinase. Isolation of Fc-SC and Fab fragments of human secretory IgA

Secretory IgA N-glycans contribute to the protection against E. coli O55 infection of germ-free piglets

Collaborators (6)

Michal Křupka

Petr Malý

Hana Petrokova

Milan Raska

Valeria Skopelidou

Marek Sinkora

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