Leonardo Scapozza

Full Professor

University of Geneva

Switzerland

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Research Interests

Pharmacology

50%

Pharmaceutical Chemistry

50%

Chemical Biology

30%

Natural Products Chemistry

30%

Tyrosine Kinase

20%

Drug Development

20%

Neuropharmacology

20%

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Recent Grants

Grant: Close

Adenosine 2A receptor reactivation by positive allosteric mod-ulators as a new therapeutic venue for unmet medical need in chronic inflammation

Open Date: 2022-09-01

Close Date: 2024-02-01

Grant: Close

A2AR negative allosteric modulators for cancer immunotherapy: validation of lead candidate

Open Date: 2020-12-01

Close Date: 2022-06-01

Grant: Close

G2B Gut-To-Blood: a platform for oral systemic delivery of targeted therapies

Open Date: 2020-01-01

Close Date: 2023-01-01

Grant: Close

Duchenne muscular dystrophy: Phenotyping and validation of better murine models for improving preclinical research and clinical translation

Open Date: 2020-01-01

Close Date: 2022-01-01

Grant: Close

Repurposing drugs to combat fibrosis in Duchenne patients: Pharmacotherapy studies in a murine model with enhanced fibrosis

Open Date: 2020-01-01

Close Date: 2022-01-01

Articles10

Identification of Natural Products Inhibiting SARS-CoV-2 by Targeting Viral Proteases: A Combined in Silico and in Vitro Approach

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Year:

2023

CEMIP (HYBID, KIAA1199): structure, function and expression in health and disease

Article Link

Year:

2023

Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1

Article Link

Year:

2023

Challenges and Opportunities in the Oral Delivery of Recombinant Biologics

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Year:

2023

In silico investigation of cytochrome bc1 molecular inhibition mechanism against Trypanosoma cruzi

Article Link

Year:

2023

Identification of non-ATP-competitive α-carboline inhibitors of the anaplastic lymphoma kinase

Article Link

Year:

2022

5-ethyl-2’-deoxyuridine fragilizes Klebsiella pneumoniae outer wall and facilitates intracellular killing by phagocytic cells

Article Link

Year:

2022

Discovery of anti-Formin-like 1 protein (FMNL1) antibodies in membranous nephropathy and other glomerular diseases.

Article Link

Year:

2022

Correction to "Discovery of Novel α-Carboline Inhibitors of the Anaplastic Lymphoma Kinase".

Article Link

Year:

2022

Discovery of Novel α-Carboline Inhibitors of the Anaplastic Lymphoma Kinase.

Article Link

Year:

2022

Collaborators18

Simon Braun

Assistant Professor

University of Geneva

SWITZERLAND

Johannes Kirchmair

Universität Wien

AUSTRIA

Pierre Cosson

SWITZERLAND

Alfonso Zambon

University of Modena and Reggio Emilia

ITALY

Sascha Hoogendoorn

University of Geneva

SWITZERLAND

Maxime CULOT

Associate professor

Université d'Artois

FRANCE

Marco Prunotto

SWITZERLAND

Fabien Gosselet

Professeurs des Universités

Université d'Artois

FRANCE

Luca Mologni

University of Milano-Bicocca

ITALY

Andreas Boland

Assistant Professor

University of Geneva

SWITZERLAND

Cédric Schneider

FRANCE

Magali Zeisser Labouebe

University of Geneva

SWITZERLAND

David Gueyrard

Professor

Université Claude Bernard Lyon 1 Faculté des Sciences et Technologies

FRANCE

Marie Jose Abi Saad

Universität Wien

AUSTRIA

Ulrike Grienke

Universität Wien

AUSTRIA

Andrea Danani

Professor

Istituto dalle Molle di Studi sull'Intelligenza Artificiale

SWITZERLAND

Judith Rollinger

Universität Wien

AUSTRIA

Jonathan P. Sleeman

Heidelberg University

GERMANY

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