Leonardo SORCI

Associate Professor

Marche Polytechnic University

Italy

Research Interests

Explore related searches

Professors in Italy Professors in Molecular Biology Molecular Biology professors in Italy

Contact this professor

Get a free first email built on one of their papers, ready for you to edit and send yourself.

About

Leonardo Sorci is an Associate Professor at Marche Polytechnic University in Italy. His research areas include the synthesis and evaluation of NAD-mimetics, protein interactions in biosynthesis, and the structural dynamics of EGFR mutants relevant to cancer therapy. He has authored several recent articles exploring enzymatic assays and molecular insights into nicotinamide metabolism and its implications for drug design.

Articles (14)

Year:

2024

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2020

Year:

2020

Year:

2020

Year:

2020

Collaborators (18)

Giacomo Corleone

ITALY

Leonardo SORCI

Research Interests

Explore related searches

Contact this professor

About

Articles (14)

Synthesis, Biological, and Computational Evaluations of Conformationally Restricted NAD-Mimics as Discriminant Inhibitors of Human NMN-Adenylyltransferase Isozymes

Periplasmic binding proteins Bug69 and Bug27 from <i>Bordetella pertussis</i> are <i>in vitro</i> high-affinity quinolinate binders with a potential role in NAD biosynthesis

Probing conformational dynamics of EGFR mutants <i>via</i> SEIRA spectroscopy: potential implications for tyrosine kinase inhibitor design

A Versatile Continuous Fluorometric Enzymatic Assay for Targeting Nicotinate Phosphoribosyltransferase

Properly Substituted Benzimidazoles as a New Promising Class of Nicotinate Phosphoribosyltransferase (NAPRT) Modulators

Molecular insights into the interaction between human nicotinamide phosphoribosyltransferase and Toll-like receptor 4

Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis

Identification of a novel nitroflavone-based scaffold for designing mutant-selective EGFR tyrosine kinase inhibitors targeting T790M and C797S resistance in advanced NSCLC

Mechanistic insight toward EGFR activation induced by ATP: role of mutations and water in ATP binding patterns

Enzymology of extracellular NAD metabolism.

Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells.

The Prospective Synergy of Antitubercular Drugs With NAD Biosynthesis Inhibitors.

Functional characterization of COG1713 (YqeK) as a novel diadenosine tetraphosphate hydrolase family

Inhibition of the NAD salvage pathway in schistosomes impairs metabolism, reproduction, and parasite survival

Collaborators (18)

Giacomo Corleone

Loredana CAPPELLACCI

Esther Kellenberger

Nadia RAFFAELLI

Stefano Amatori

Valentina Audrito

Michele Cianci

Fabio Del Bello

Vladia Monsurrò

Roberta Galeazzi

Michele Guescini

Laura Graciotti

Emiliano Laudadio

Giuseppe Orsomando

Gianfabio Giorgioni

Riccardo Petrelli

Cristina Minnelli

Santina Bruzzone

Make your next move.