Leonid Metelitsa

Professor

Baylor College of Medicine

United States

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Leonid Metelitsa is a Professor at Baylor College of Medicine in the United States. His research focuses on natural killer T cells and their applications in cancer therapies, as evidenced by his recent articles on topics such as CAR-expressing NKT cells and tumor immunology. He is particularly interested in the mechanisms underlying antitumor activity and the development of treatment strategies for various malignancies.

Articles (11)

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2025

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2021

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2021

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2020

Collaborators (3)

Xin Xu

Assistant Professor

Baylor College of Medicine

UNITED STATES

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Ketan Ghaghada

Assistant Professor and Manager of Basic Science Research Program

Texas Children's Hospital

UNITED STATES

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Ananth Annapragada

Professor and Director of Basic Research

Texas Children's Hospital

UNITED STATES

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Leonid Metelitsa

Research Interests

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Articles (11)

A milestone method to make natural killer T cells

IL-12 reprograms CAR-expressing natural killer T cells to long-lived Th1-polarized cells with potent antitumor activity

LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells

Natural killer T cells and other innate-like T lymphocytes as emerging platforms for allogeneic cancer cell therapy

Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results

Interaction between tumor cell TNFR2 and monocyte membrane-bound TNF-α triggers tumorigenic inflammation in neuroblastoma

Refining chimeric antigen receptors via barcoded protein domain combination pooled screening

Long-term follow-up for the development of subsequent malignancies in patients treated with genetically modified IECs

A Nanoradiomics Approach for Differentiation of Tumors Based on Tumor-Associated Macrophage Burden

Allogeneic NKT Cells Expressing a CD19-Specific CAR in Patients with Relapsed or Refractory B-Cell Malignancies: An Interim Analysis

A High-Avidity T-cell Receptor Redirects Natural Killer T-cell Specificity and Outcompetes the Endogenous Invariant T-cell Receptor

Collaborators (3)

Xin Xu

Ketan Ghaghada

Ananth Annapragada

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