Leslie A. Will
Chair and Anthony A. Gianelly Professor
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About
Leslie A. Will is the Chair and Anthony A. Gianelly Professor at the Boston Foundation in the United States. His research areas include oral health-related quality of life, craniofacial shape analysis, and the effects of surgical interventions on airway dynamics. Additionally, he investigates the heritability of facial soft tissue growth and evidence-based research methodologies among orthodontic postgraduate residents. His recent contributions to the field highlight the intersection of genetics, surgery, and orthodontics.
Articles (7)
Year:
2025
Year:
2025
Objective The aim of this study was to evaluate the long‐term volumetric changes of the upper airway compartments in response to counterclockwise bimaxillary advancement surgery with multi‐piece maxillary osteotomy, and to analyse the relationship between the postoperative stability of the maxillomandibular skeletal complex, and the volumetric airway changes over‐time. Methodology Twenty‐seven sets of pre (T0), post (T1) and follow‐up (T2) (20.15 months) CBCT scans were used. The upper airway was isolated into five compartments: soft and bony nasal cavity (SNC, BNC), nasopharynx (NP), oropharynx (OP) and hypopharynx (HP) using Mimics V.22 software. The volumetric changes and the correlation between the airway change and the skeletal movements were analysed using repeated measure ANOVA, and Pearson's correlation coefficient, respectively. Results The results showed a significant decrease in SNC and BNC (10.94% and 7.69%, p < .05) at T1. However, SNC presented a significant recovery (11.73%, p < .05) at T2. NP, OP and HP segments presented significant and stable increases over time (10.41%, 53.62%, 24.70%, p < .05). Conclusions This surgical approach produced a significant increase in OP and HP volumes in short and long term without a significant relapse, NP showed a significant increase in long term only, SNC and BNC volumes showed a significant decrease post‐surgery which was only partially maintained for BNC.
Year:
2023
Year:
2023
Year:
2022
Year:
2022
Year:
2020
Collaborators (4)
Melih Motro
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Marianne Saade
Boston University
Pushkar Mehra
Professor and Chair
Boston University
Despina Koletsi
University of Zurich
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