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Lisa Saksida

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Scientist and Scientific Director, BrainsCAN

Western University

Canada

Research Interests

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Professors in Canada Professors in Neuropsychology Neuropsychology professors in Canada

Recent Grants

Grant: Close

Mouse Translational Research Accelerator Platform (MouseTRAP)

Open Date: 2023-06-12

Close Date:

Grant: Close

MouseTRAP: The Mouse Translational Research Accelerator Platform

Open Date: 2022-04-01

Close Date:

Grant: Close

TRIDENT: TRanslational Initiative to DE-risk NeuroTherapeutics

Open Date: 2022-04-01

Close Date: 2023-03-31

Grant: Close

Interactions between hippocampal vesicular acetylcholine transporter (VAChT) loss and amyloid pathology in circuit and cognitive deficits in Alzheimer's disease

Open Date: 2022-03-01

Close Date: 2023-02-28

Grant: Close

Neurochemical basis of high-level cognitive function in health and disease

Open Date: 2021-09-02

Close Date: 2026-09-01

Articles (20)

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Collaborators (10)

Laura Lopez-Cruz

Open University

UNITED KINGDOM

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Ravi Menon

Professor

Western University

CANADA

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Paul Sheppard

Research Associate

Western University

CANADA

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Takaomi Saido

Team Leader

RIKEN Center for Brain Science

JAPAN

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R. J. Rylett

CANADA

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Marco Antonio Maximo Prado

Scientist, Professor

University of Western Ontario

CANADA

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Tim Bussey

Professor and Western Research Chair in Behavioural Neuroscience

University of Western Ontario

CANADA

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Takashi Saito

Professor

University of Tokyo

JAPAN

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Olamide Adebiyi

Assistant Professor

University of Saskatchewan

CANADA

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Wataru Inoue

Scientist, Associate Professor

Western University

CANADA

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Lisa Saksida

Research Interests

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Recent Grants

Articles (20)

A dual role of hippocampal perineuronal nets in plasticity and protection is revealed by improvement and impairment of diet-induced memory dysfunction

Citric acid water as an alternative to food restriction to motivate task performance in mice during touchscreen testing

Prefrontal parvalbumin neurons as a target for enhancing cognition in non-pathological and 22q11.2 microdeletion syndrome mice

Characterisation of a touchscreen-based task for assessing cognitive judgement bias in mice: a new translational tool for affective state disorder drug screening

From adaptive to maladaptive myelination: White matter dynamics in cognition and neurologic disorders

Differential contributions of striatal dopaminergic pathways to visuomotor conditional learning.

Integrating optical neuroscience tools into touchscreen operant systems

Characterization of a novel transgenic mouse model to investigate brain-wide activation of astrocyte Gq signaling

Impaired Cognitive Flexibility With Preserved Learning in an Amyloid Precursor Protein Knock‐In Mouse Model of Amyloidopathy

Apolipoprotein E (ApoE) 4 exacerbates pattern separation deficits and amyloid pathology in a combined humanized knock‐in Apolipoprotein E, Amyloid, and Tau model of Alzheimer's Disease

Characterization of mouse models of synucleinopathies

Evaluating the Efficacy and Risks of Early Lecanemab Treatment in APOE4 Humanized Alzheimer's Disease Mouse Models

Reduced cholinergic tone and hippocampal‐dependent cognitive impairments in APPNL‐F mice

Resistance exercise improves working memory, but not set shifting in older adults at risk for diabetes

STIP1 Knockout Mitigates Disease Progression in a Synucleinopathy Mouse Model: A Multimodal Behavioral and Neuroimaging Study

TRanslational Initiative to DE‐risk NeuroTherapeutics (TRIDENT) – A revolutionary pre‐clinical approach to maximize the predictive validity of pre‐clinical evaluation

Tau pathology in triple knock‐in mouse model of Alzheimer's Disease expressing APOE3 and APOE4

The Multifactorial Impact of ApoE4 on Alzheimer's Pathology and Cognitive Decline

Translational cognitive biomarkers for preclinical drug testing in neurodegenerative diseases

Increases to Subfields of the Hippocampus Following Resistance Exercise Correlate With Improved Cognition in Older Adults at Risk for Type 2 Diabetes

Collaborators (10)

Laura Lopez-Cruz

Ravi Menon

Paul Sheppard

Takaomi Saido

R. J. Rylett

Marco Antonio Maximo Prado

Tim Bussey

Takashi Saito

Olamide Adebiyi

Wataru Inoue

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