Lori Isom

Maurice H. Seevers Professor and Chair of Pharmacology

University of Michigan Medical School

United States

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Articles (12)

Year:

2024

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2024

Year:

2024

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2022

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2022

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2021

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (9)

April Lukowski

University of Michigan

UNITED STATES

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Juliet Knowles

department of neurology university of michigan ann arbor usa

UNITED STATES

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Alfred L George

Northwestern University Feinberg School of Medicine

UNITED STATES

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Paul Jenkins

Assistant Professor

University of Michigan

UNITED STATES

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Holger Lerche

GERMANY

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Daniel H. Lowenstein

UNITED STATES

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Johannes W Hell

Professor

University of California, Davis

UNITED STATES

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Ethan Goldberg

Associate Professor

University of Pennsylvania Perelman School of Medicine

UNITED STATES

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Cameron S. Metcalf

University of Utah

UNITED STATES

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Lori Isom

Research Interests

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Articles (12)

Memorial Tribute to William Albert Catterall (1946–2024)

William Albert Catterall (1946–2024)

Antisense oligonucleotides restore excitability, GABA signalling and sodium current density in a Dravet syndrome model

Precision medicine for genetic epilepsy on the horizon: Recent advances, present challenges, and suggestions for continued progress

Therapeutic Potential of Targeting Regulated Intramembrane Proteolysis Mechanisms of Voltage-Gated Ion Channel Subunits and Cell Adhesion Molecules

Gastrointestinal Symptoms and Channelopathy-Associated Epilepsy

Dravet Syndrome: Novel Approaches for the Most Common Genetic Epilepsy

Modulation of the effects of Class-Ib antiarrhythmics on cardiac NaV1.5-encoded channels by accessory NaVβ subunits

Sodium channel β1 subunits participate in regulated intramembrane proteolysis-excitation coupling

Sodium channel β1 subunits are post-translationally modified by tyrosine phosphorylation, S-palmitoylation, and regulated intramembrane proteolysis

Excitatory and inhibitory neuron defects in a mouse model of Scn1b‐linked EIEE52

The voltage-gated sodium channel inhibitor, 4,9-anhydrotetrodotoxin, blocks human Nav1.1 in addition to Nav1.6

Collaborators (9)

April Lukowski

Juliet Knowles

Alfred L George

Paul Jenkins

Holger Lerche

Daniel H. Lowenstein

Johannes W Hell

Ethan Goldberg

Cameron S. Metcalf

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