Lu Chen

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Assistant Professor

Fox Chase Cancer Center

United States

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Recent Grants

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How a noncoding driver mutation drives cancer immortality

Open Date: 2018-07-01

Close Date: 2019-07-01

Articles (8)

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2022

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2022

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2021

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2021

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2021

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2021

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2020

Year:

2020

Collaborators (6)

isabella saggio

Asscoiate professor and Lab head

Università degli Studi di Roma La Sapienza

ITALY

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Grazia D Raffa

Sapienza University of Rome

ITALY

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Brunhilde Wirth

University Hospital Bonn

GERMANY

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Ameen A Salahudeen

Assistant Professor

University of Chicago

UNITED STATES

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Calvin Kuo

Professor

Stanford University

UNITED STATES

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Paolo Maccallini

Sapienza University of Rome

ITALY

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Lu Chen

Research Interests

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Recent Grants

Articles (8)

TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration.

TGS1 impacts snRNA 3 '-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration

Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus

A novel DDB2 mutation causes defective recognition of UV-induced DNA damages and prevalent equine squamous cell carcinoma

Analysis of RNA conformation in endogenously assembled RNPs by icSHAPE

Clonal inactivation of telomerase promotes accelerated stem cell differentiation

Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation

TGS1 controls snRNA 3’ end processing, prevents neurodegeneration and ameliorates SMN-dependent neurological phenotypes in vivo

Collaborators (6)

isabella saggio

Grazia D Raffa

Brunhilde Wirth

Ameen A Salahudeen

Calvin Kuo

Paolo Maccallini

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