Luc Pellerin

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Professeur des Universités

University of Poitiers

France

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Luc Pellerin is a Professeur des Universités at Université de Poitiers, France. His research focuses on metabolomics, neurobiology, and the metabolic processes affecting cognitive functions and diseases. Recent publications include studies on the predictive power of machine learning in disease severity, the role of glycolysis in cognitive processes, and metabolic alterations in neurodegenerative conditions.

Recent Grants

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An in vivo exploration of the metabolic coupling between glial cells and neurons upon cerebral activation and its importance for synaptic plasticity using cutting edge NMR spectroscopy approaches

Open Date: 2016-01-01

Close Date: 2018-12-31

Grant: Close

Role of non-glycolytic energy substrates in supporting synaptic vesicles cycling

Open Date: 2013-09-01

Close Date: 2013-11-30

Grant: Close

FGF21 is a link between reproduction and energy balance

Open Date: 2012-12-01

Close Date: 2016-05-31

Grant: Close

Monocarboxylate transporters in the central nervous system: a study of their distribution, regulation of expression and cell-specific roles

Open Date: 2012-04-01

Close Date: 2015-03-31

Grant: Close

Monocarboxylate transporters in the central nervous system: a study of their distribution, regulation of expression and cell-specific roles

Open Date: 2009-04-01

Close Date: 2012-04-30

Articles (20)

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2021

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2021

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2021

Collaborators (13)

Kourosh Saeb-Parsy

Reader

University of Cambridge

UNITED KINGDOM

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Carla CANNIZZARO

Full Professor

University of Palermo

ITALY

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camilla svensson

Karolinska Institutet

SWEDEN

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Igor Camargo Fontana

Karolinska Institutet

SWEDEN

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Jean-François Tanti

CNRS Délégation Côte d'Azur

FRANCE

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Lorenz Hirt

Professeur associé médecin adjoint

Centre Hospitalier Universitaire Vaudois

SWITZERLAND

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sebastien giraud

Inserm u1183

FRANCE

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Eva Hedlund

Professor

Stockholm University

SWEDEN

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Michael Shattock

King’s College London

UNITED KINGDOM

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Stephen Carter

Karolinska University Hospital

SWEDEN

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Thierry Hauet

Professor

University of Poitiers

FRANCE

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Nicolas Melis

Junior Professor

University of Poitiers

FRANCE

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PEDRO ROSA-NETO

Professor

McGill University

CANADA

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Luc Pellerin

Research Interests

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About

Recent Grants

Articles (20)

Neuroprotective effects of lactate and ketone bodies in acute brain injury

A lactate-dependent shift of glycolysis mediates synaptic and cognitive processes in male mice.

Advantages of Metabolomics-Based Multivariate Machine Learning to Predict Disease Severity: Example of COVID

Astrocytic metabolic control of orexinergic activity in the lateral hypothalamus regulates sleep and wake architecture

Elevation of hypothalamic ketone bodies induces a decrease in energy expenditures and an increase risk of metabolic disorder

Corrigendum to "Elevation of hypothalamic ketone bodies induces a decrease in energy expenditures and an increase risk of metabolic disorder" [Mol Metab, 83 (2024) 101926].

Early rise of glutamate-glutamine levels in mild cognitive impairment: Evidence for emerging excitotoxicity

Reply to: “Is NAFLD a key driver of brain dysfunction?”

Diagnostic and Therapeutic Issues in Glioma Using Imaging Data: The Challenge of Numerical Twinning

Early Metabolic Alteration Predicts Outcome With Middle Cerebral Artery Occlusion Treated by Mechanical Thrombectomy

Identification of Intron Retention in the Slc16a3 Gene Transcript Encoding the Transporter MCT4 in the Brain of Aged and Alzheimer-Disease Model (APPswePS1dE9) Mice

Comment on “Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases”

Bisphenol S favors hepatic steatosis development via an upregulation of liver MCT1 expression and an impairment of the mitochondrial respiratory system

Disrupted function of lactate transporter MCT1, but not MCT4, in Schwann cells affects the maintenance of motor end-plate innervation

About the source and consequences of 18F-FDG brain PET hypometabolism in short and long COVID-19

Mechanism of succinate efflux upon reperfusion of the ischaemic heart

Astrocyte Biomarkers in Alzheimer Disease

Inhibition of eIF5A hypusination reprogrammes metabolism and glucose handling in mouse kidney.

Altered mrna and protein expression of monocarboxylate transporter mct1 in the cerebral cortex and cerebellum of prion protein knockout mice

Lactate fluxes mediated by the monocarboxylate transporter-1 are key determinants of the metabolic activity of beige adipocytes

Collaborators (13)

Kourosh Saeb-Parsy

Carla CANNIZZARO

camilla svensson

Igor Camargo Fontana

Jean-François Tanti

Lorenz Hirt

sebastien giraud

Eva Hedlund

Michael Shattock

Stephen Carter

Thierry Hauet

Nicolas Melis

PEDRO ROSA-NETO

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