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Luca Giliberto

Has grant

Associate Professor

Donald & Barbara Zucker School of Medicine at Hofstra/Northwell

United States

Research Interests

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Recent Grants

Grant: Close

New role(s) for IRF5 as a regulator of tau accumulation in Alzheimer’s disease

Open Date: 2021-09-15

Close Date: 2024-05-31

Grant: Close

Vectorized scFv antibodies to treat tau pathology in Alzheimer's disease: enhancing epitope targeting and delivery strategies

Open Date: 2020-09-15

Close Date: 2026-05-31

Grant: Close

Gene Therapy for Alzheimer's Disease

Open Date: 2019-10-01

Close Date: 2020-09-30

Grant: Close

Novel Cognitive and Functional Measure for Alzheimer's Disease Prevention Trials

Open Date: 2018-09-01

Close Date: 2026-05-31

Grant: Close

Immunotherapy in Alzheimer's Disease Animal Models Using Tau Recombinant Antibodies

Open Date: 2017-09-30

Close Date: 2019-08-31

Articles (20)

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Collaborators (8)

Mario Passalacqua

Ricercatore confermato

University of Genoa

ITALY

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Wentian Li

Stony Brook University

UNITED STATES

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Yilong Ma

Director of PET Imaging Core

Feinstein Institute for Medical Research

UNITED STATES

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Jesus Gomar

Assistant Professor

Feinstein Institute for Medical Research

UNITED STATES

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Luciano D'Adamio

Professor

Rutgers University

UNITED STATES

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Marina Sartini

University of Genoa

ITALY

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Daniel M. Sciubba

Chairman of Neurosurgery

Northwell Health

UNITED STATES

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Ana Franceschi, M.D., PH.D.

Director of Molecular Neuroimaging

Northwell Health

UNITED STATES

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Luca Giliberto

Research Interests

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Recent Grants

Articles (20)

Heme Oxygenase-1 Contributes to Dampening Proinflammatory Activation in the Human Microglial Cell Line HMC3 and Controls the Transcription Factor IRF5

Endogenous neuroprotection in vascular cognitive impairment and dementia

Differential associations of APOE and TREM2 variants with glial fibrillary acidic protein and neurofilament light in plasma of UK Biobank participants support distinct disease mechanisms

AhR, IRF5, and HO‐1 Expression in Evaluating Carotid Atherosclerotic Plaque Vulnerability: A Pilot Observational Study

Non-Electrophilic Activation of NRF2 in Neurological Disorders: Therapeutic Promise of Non-Pharmacological Strategies

AAV-mediated peripheral scFv's administration to reduce cerebral tau in adult P301S transgenic mice: Mono-vs. combination therapy

AAV-mediated peripheral single chain variable fragments administration to reduce cerebral tau in adult P301S transgenic mice: mono- vs combination therapy

APOE and TREM2 variants differentially influence glial fibrillary acidic protein and neurofilament light in plasma of UK Biobank participants

Heme oxygenase-1 counteracts proinflammatory activation of microglial cells by acting on IRF5

An Open-Label, Pilot Study of Daratumumab SC in Mild to Moderate Alzheimer's Disease.

Analysis of early effects of human APOE isoforms on Alzheimer's disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOE

Analysis of early effects of human APOE isoforms on Alzheimer's disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOE (vol 22, 458, 2024)

Creutzfeldt-Jakob disease presenting as psychiatric disorder: case presentation and systematic review

Memories and mimics: unveiling the potential of FDG-PET in guiding therapeutic approaches for neurodegenerative cognitive disorders

18F-FDG Brain PET/MRI in Amyotrophic Lateral Sclerosis– Frontotemporal Spectrum Disorder (ALS-FTSD)

Semiquantitative Approach to Amyloid Positron Emission Tomography Interpretation in Clinical Practice

Aβ43 levels determine the onset of pathological amyloid deposition

Interferon regulatory factor 5 modulates microglia response to tau by interfering with phagocytosis

Bridging Machine Learning and Clinical Diagnosis: An Explainable Biomarker for ß-Amyloid PET Imaging

NRF2/HO-1 PATHWAY LIMITS TLR4-AND TLR7/8-DEPENDENT IRF5 ACTIVATION IN MACROPHAGE-LIKE CELLS

Collaborators (8)

Mario Passalacqua

Wentian Li

Yilong Ma

Jesus Gomar

Luciano D'Adamio

Marina Sartini

Daniel M. Sciubba

Ana Franceschi, M.D., PH.D.

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