Luciano Giaco'

Head of Bioinformatics

Policlinico Universitario Agostino Gemelli

Italy

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About

Luciano Giaco' is the Head of Bioinformatics at Policlinico Universitario Agostino Gemelli in Italy. His research focuses on genomics and bioinformatics in oncology, with recent publications addressing topics such as BRCA genomic rearrangements, intratumor heterogeneity in pituitary tumors, and pharmacogenetic models for lung cancer treatment reactions. He is also actively involved in the characterization of neoantigens in endometrial cancer and the development of analysis pipelines for spatial profiling imaging data.

Articles (18)

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2025

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2021

Collaborators (12)

Emilio Bria

Associate Professor

Università Cattolica del Sacro Cuore

ITALY

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Anna Fagotti

Associate Professor

ITALY

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antonio ruggiero

Agostino Gemelli University Polyclinic

ITALY

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Angelo Minucci

University of Padova

ITALY

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Marianna BUTTARELLI

Assistant Professor (tenure track)

University of Rome Tor Vergata

ITALY

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Frediano Inzani

Università degli Studi di Pavia

ITALY

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Martina Rinelli

ITALY

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Antonio Giordano

Professor and DIrector

Temple University

UNITED STATES

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Daniela Gallo

Dirigente Sanitario I livello - Head of Unit of Translational Medicine for Woman and Child Health

Università Cattolica del Sacro Cuore Facoltà di Medicina e Chirurgia

ITALY

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Fiorella Gurrieri

ITALY

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vittoria rufini

Associate Professor

Università Cattolica del Sacro Cuore

ITALY

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Riziero Esposito Abate

Fondazione IRCCS Istituto Nazionale dei Tumori

ITALY

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Luciano Giaco'

Research Interests

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Articles (18)

Detection of Clinically Significant BRCA Large Genomic Rearrangements in FFPE Ovarian Cancer Samples: A Comparative NGS Study

Spatial Analysis Identifies CD147 as a Novel Marker of High-Grade Childhood Posterior Fossa Ependymoma

Oncological Treatment Adverse Reaction Prediction: Development and Initial Validation of a Pharmacogenetic Model in Non-Small-Cell Lung Cancer Patients

POLE mutations in endometrial carcinoma: Clinical and genomic landscape from a large prospective single‐center cohort

Identification of a False-positive Multiplex Ligationdependent Probe Amplification Result in BRCA1 Using a Copy Number Variation Algorithm Under Development for a Commercial Next-Generation Sequencing-based Homologous Recombination Deficiency Assay

LCM-RNAseq Highlights Intratumor Heterogeneity and a lncRNA Signature from Archival Tissues of GH-Secreting PitNETs

Germline reflex BRCA1/2 testing following tumor-only comprehensive genomic profiling: why, when, and how

ALOA, a pipeline for preliminary analysis of spatial profiling imaging data

Characterization of shared neoantigens landscape in Mismatch Repair Deficient Endometrial Cancer

Impact of Comprehensive Genome Profiling on the Management of Advanced Non–Small Cell Lung Cancer: Preliminary Results From the Lung Cancer Cohort of the FPG500 Program

Identification by Exome Sequencing of Predisposing Variants in Familial Cases of Autoinflammatory Recurrent Fevers

Evaluating the Risk of Inguinal Lymph Node Metastases before Surgery Using the Morphonode Predictive Model: A Prospective Diagnostic Study in Vulvar Cancer Patients

Bioinformatics: From NGS Data to Biological Complexity in Variant Detection and Oncological Clinical Practice

A Computational Framework for Comprehensive Genomic Profiling in Solid Cancers: The Analytical Performance of a High-Throughput Assay for Small and Copy Number Variants

Identification of a novel gene signature predicting response to first-line chemotherapy in BRCA wild-type high-grade serous ovarian cancer patients

Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center

The impact of the COVID-19 pandemic on oncological disease extent at FDG PET/CT staging: the ONCOVIPET study.

The Vulvar Immunohistochemical Panel (VIP) Project: Molecular Profiles of Vulvar Squamous Cell Carcinoma

Collaborators (12)

Emilio Bria

Anna Fagotti

antonio ruggiero

Angelo Minucci

Marianna BUTTARELLI

Frediano Inzani

Martina Rinelli

Antonio Giordano

Daniela Gallo

Fiorella Gurrieri

vittoria rufini

Riziero Esposito Abate

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