Ludovic Vallier

Professor

Berlin Institute of Health at Charité - Universitätsmedizin Berlin

Germany

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Professor Ludovic Vallier is a faculty member at the Berlin Institute of Health in Germany. His research primarily focuses on the mechanisms underlying cholangiocyte plasticity and its implications for liver disorders, as evidenced by his recent publications on topics such as transdifferentiation of cholangiocytes and cell therapy for liver conditions. Additionally, he explores the functional dynamics of human epithelial cells in relation to chronic liver disease and cellular metabolism.

Articles (20)

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2025

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2022

Collaborators (18)

William Scott

Senior Lecturer

Newcastle University

UNITED KINGDOM

Ludovic Vallier

Research Interests

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Articles (20)

Transcriptomic and epigenetic mechanisms controlling cholangiocytes transdifferentiation into hepatocytes

Plasticité épithéliale dans les maladies hépatiques chroniques

Cell therapy for liver disorders: past, present and future

Reactive cholangiocyte-derived ORM2 drives a pathogenic modulation of the injured biliary niche through macrophage reprogramming.

Acquisition of epithelial plasticity in human chronic liver disease

Single-Cell Transcriptomic Profiling of Cholangiocyte Organoids Derived from Bile Ducts of Primary Sclerosing Cholangitis Patients.

In vitro platform to model the function of ionocytes in the human airway epithelium

Exploiting the plasticity of cholangiocytes to repair the biliary tree

Human surface ectoderm and amniotic ectoderm are sequentially specified according to cellular density

Limited oxygen in standard cell culture alters metabolism and function of differentiated cells.

FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2

Modeling Nonalcoholic Fatty Liver Disease in the Dish Using Human-Specific Platforms: Strategies and Limitations.

Human branching cholangiocyte organoids recapitulate functional bile duct formation

Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance

A single-cell comparison of adult and fetal human epicardium defines the age-associated changes in epicardial activity.

Derivation of Multipotent Neural Progenitors from Human Embryonic Stem Cells for Cell Therapy and Biomedical Applications.

Deterministic programming of human pluripotent stem cells into microglia facilitates studying their role in health and disease.

Generation of functional hepatocytes by forward programming with nuclear receptors.

Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells.

Single-cell atlas of human liver development reveals pathways directing hepatic cell fates.

Collaborators (18)

William Scott

Matthias Pawlowski

Tobias Puengel

Milad Rezvani

Marta Vilà González

Stephen Pereira

Christopher Watson

Andrew M. Moon

David Schafflick

Simon Buczacki

Oskar Rosmark

Krista Rombouts

Jan Tchorz

James Stewart

Richard Bartfai

Christian Thomas

Vessela Vassileva

Espen Melum

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