Luigi Vaccaro

We have defined a procedure for the late‐stage functionalization of aryl borazines to facilitate the synthesis of a diverse array of borazine derivatives with varying substitution patterns, paving the way for further exploration of the field. More in detail, we have studied and disclosed a simple iodination procedure that could be applied to several differently substituted substrates ( 1 a – i ) with mostly good to excellent yields (47–96%). The representative iodinated compounds 2 b and 2 e , were utilized to test their use in further representative functionalization steps such as cyanation, Heck, and Sonogashira reactions. All products 3 a – e were obtained in satisfactory good to very good yields considering the multiple (three or six times) concomitant reactions.