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Luis Alvarez-Vallina

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Group Leader and Director of the Advanced Therapy Programme

Institut Hospital del Mar d'Investigacions Mèdiques

Spain

Research Interests

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Professors in Spain Professors in Immunology Immunology professors in Spain

Recent Grants

Grant: Close

GENERATION OF ANTI4-1BB x ANTI-PD-L1 BISPECIFIC IMMUNOSTIMULATORY TRIMERBODIES FOR CANCER THERAPY

Open Date: 2016-01-01

Close Date: 2016-12-31

Grant: Close

Applying collagen-based multimerizing scaffolds for translating membrane-interacting immunosuppressive viral peptides into drug candidates

Open Date: 2014-11-01

Close Date: 2017-10-31

Articles (20)

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2023

Collaborators (22)

Eduardo Anguita Mandly

Professor (Profesor Titular)

Universidad Complutense de Madrid

SPAIN

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Manel Juan

Head of Immunology service/department

Hospital Clínic de Barcelona

SPAIN

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Alba Pérez Pons

University of Salamanca

SPAIN

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Julio Delgado

Head

Hospital Clínic de Barcelona

SPAIN

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Ines Munoz

Head of Unit (Protein Crystallography Unit)

Centro Nacional de Investigaciones Oncológicas

SPAIN

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Delvys Rodriguez-Abreu

Universidad de Las Palmas de Gran Canaria

SPAIN

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Ana Arance

University of Barcelona

SPAIN

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Francisco Blanco

INSTITUTO DE BIOMEDICINA DE VALENCIA

SPAIN

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Rodolfo Chicas-Sett

Faculty

Hospital Universitari i Politècnic La Fe

SPAIN

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Antonio Valeri

Senior Researcher

Instituto de Investigación Hospital 12 de Octubre

SPAIN

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PABLO VELASCO

Department Associate Professor

University of Barcelona

SPAIN

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martin villalba

CNRS Délégation Languedoc-Roussillon

FRANCE

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Marwa Elkhashab

Teaching assistant

University of Sadat City

EGYPT

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Mireia Pelegrin

CNRS Researcher, Group Leader of "Antibodies and Immunomodulation"

INSERM

FRANCE

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Sandra Rodriguez-Perales

Head of Molecular Cytogenetics & Genome Editing Unit

Centro Nacional de Investigaciones Oncológicas

SPAIN

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Carlos Alfonso

Staff Scientists

Centro de Investigaciones Biológicas Margarita Salas

SPAIN

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Laura Sanz

Lab Head

SPAIN

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Martin R. Jakobsen

VIP, Professor

Aarhus University

DENMARK

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Ian Helstrup Nielsen

Aarhus University

DENMARK

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Søren Degn

VIP, Associate Professor

Aarhus University

DENMARK

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Aïda Falgàs

Hospital de la Santa Creu i Sant Pau

SPAIN

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Seandean Lykke Harwood

Assistant Professor

Aarhus University

DENMARK

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Luis Alvarez-Vallina

Research Interests

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Recent Grants

Articles (20)

Abstracts of the XII Forum on Translational Immunology and Cancer Immunotherapy (FIT Cancer 12)

Cell-delivered CD3×CD19 T-cell engager by STAb-T19 cells mediates leukemia clearance with limited systemic exposure

CD22 CAR-T cells secreting CD19 T-cell engagers for improved control of B-cell acute lymphoblastic leukemia progression

A TIM-3-Fc decoy secreted by engineered T cells improves CD19 CAR-T cell therapy in B-cell acute lymphoblastic leukemia

Exploiting FcRn engagement of an albumin-CpG oligonucleotide covalent conjugate for potent TLR9 immune induction

Simultaneous secretion of a PD-L1 x 4-1BB bispecific antibody improves antileukemic efficacy of STAb-T cells secreting a CD19-specific T-cell engager

Abstracts of the XI Forum on Translational Immunology and Cancer Immunotherapy (FIT Cancer 11)

Abstracts of the X Forum on Translational Immunology and Cancer Immunotherapy (FIT Cancer 10)

Dual-targeted STAb-T cells secreting BCMA and CD19 T cell engagers for improved control of haematological cancers

mRNA-engineered T lymphocytes secreting bispecific T cell engagers with therapeutic potential in solid tumors.

Bispecific antibodies and nanotechnology: a strategic alliance in cancer immunotherapy.

Generation and functional evaluation of STAb-T cells.

Engineered T cells secreting anti-BCMA T cell engagers control multiple myeloma and promote immune memory in vivo

Characterization of a Trispecific PD-L1 Blocking Antibody That Exhibits EGFR-Conditional 4-1BB Agonist Activity

A PD-L1/EGFR bispecific antibody combines immune checkpoint blockade and direct anti-cancer action for an enhanced anti-tumor response

Dendritic Cell‐Mediated Cross‐Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS‐CoV‐2

Bi- and trispecific immune cell engagers for immunotherapy of hematological malignancies

When three is not a crowd: trispecific antibodies for enhanced cancer immunotherapy

10th antibody industrial symposium: new developments in antibody and adoptive cell therapies

Treatment of advanced or metastatic triple-negative breast cancer with adoptive therapy of PD1+tumor-infiltrating lymphocytes (TILS001 trial)

Collaborators (22)

Eduardo Anguita Mandly

Manel Juan

Alba Pérez Pons

Julio Delgado

Ines Munoz

Delvys Rodriguez-Abreu

Ana Arance

Francisco Blanco

Rodolfo Chicas-Sett

Antonio Valeri

PABLO VELASCO

martin villalba

Marwa Elkhashab

Mireia Pelegrin

Sandra Rodriguez-Perales

Carlos Alfonso

Laura Sanz

Martin R. Jakobsen

Ian Helstrup Nielsen

Søren Degn

Aïda Falgàs

Seandean Lykke Harwood

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