Luke Judge

Associate Professor

University of California, San Francisco

United States

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About

Luke Judge is an Associate Professor at the University of California, San Francisco. His research focuses on gene editing, neuromuscular junction biology, and the molecular mechanisms underlying myofibrillar myopathy and heart failure. Recent publications include investigations into BAG3 mutations, functional analysis of protective alleles against heart failure, and innovative bioengineering techniques for studying human disease models.

Articles (5)

Year:

2024

Year:

2023

Year:

2021

Year:

2021

Year:

2020

Collaborators (3)

Bruce Conklin

Professor

University of California, San Francisco

UNITED STATES

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Yuichiro Miyaoka

Ochanomizu University

JAPAN

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Hana Ghanim

Gladstone Institutes

UNITED STATES

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Luke Judge

Research Interests

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Articles (5)

Generation and characterization of an isogenic control line by correcting the BAG3 P209L mutation of a human induced pluripotent stem cell (hiPSC) line from a patient with myofibrillar myopathy-6.

Functional analysis of a common BAG3 allele associated with protection from heart failure.

Allele-Specific Gene Editing Rescues Pathology in a Human Model of Charcot-Marie-Tooth Disease Type 2E

Bioengineered optogenetic model of human neuromuscular junction.

Rapid, precise quantification of large DNA excisions and inversions by ddPCR

Collaborators (3)

Bruce Conklin

Yuichiro Miyaoka

Hana Ghanim

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