Luoni Mirko

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National Neuroscience Institute

Italy

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Recent Grants

Grant: Open

MeCP2: a double-edged sword in Rett syndrome gene therapy

Open Date: 2025-01-01

Close Date: 2028-01-01

Grant: Close

Novel gene therapy platform for “on demand” release of therapeutic cytokines for Parkinson’s disease

Open Date: 2023-01-01

Close Date: 2026-01-01

Articles (10)

Year:

2024

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2024

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2023

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2023

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2023

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2023

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2022

Year:

2022

Year:

2022

Year:

2021

Collaborators (3)

Olga Corti

INSERM

FRANCE

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Mickael GUILBAUD

Université de Nantes

FRANCE

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Jochen Prehn

Royal College of Surgeons in Ireland

IRELAND

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Luoni Mirko

Research Interests

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Recent Grants

Articles (10)

Microglia-specific <i>IL-10</i> gene delivery inhibits neuroinflammation and neurodegeneration in a mouse model of Parkinson’s disease

New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets

Intrathymic AAV delivery results in therapeutic site-specific integration at TCR loci in mice.

Genome-wide screening in pluripotent cells identifies Mtf1 as a suppressor of mutant huntingtin toxicity

MCT1-dependent energetic failure and neuroinflammation underlie optic nerve degeneration in Wolfram syndrome mice

MCT1-dependent energetic failure and neuroinflammation underlie optic nerve degeneration in Wolfram syndrome mice

Modeling native and seeded Synuclein aggregation and related cellular dysfunctions in dopaminergic neurons derived by a new set of isogenic iPSC lines with SNCA multiplications

Region-Specific KCC2 Rescue by rhIGF-1 and Oxytocin in a Mouse Model of Rett Syndrome

Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome

Author Correction: Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity

Collaborators (3)

Olga Corti

Mickael GUILBAUD

Jochen Prehn

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