Lutz Schmitt

Full Professor

Heinrich Heine University Düsseldorf

Germany

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Professor Lutz Schmitt is a Full Professor at Heinrich-Heine-Universität Düsseldorf, Germany. His research areas focus on enzyme mechanisms, substrate translocation, and the behavior of toxins at cell membranes. Recent publications investigate the structural dynamics of dehydratases, efforts to optimize secretion systems in bacteria, and the impact of macromolecular crowding on lipid interfaces.

Articles (13)

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2025

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2024

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

Collaborators (5)

Andrzej Harris

Associate Professor

University of Cambridge

UNITED KINGDOM

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Ulrich Schwaneberg

RWTH Aachen University

GERMANY

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Michael Feldbrügge

Heinrich Heine University Düsseldorf

GERMANY

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Mehdi D. Davari

GERMANY

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Ben Luisi

professor

University of Cambridge

UNITED KINGDOM

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Lutz Schmitt

Research Interests

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Articles (13)

Structural insights into the substrate binding mechanism of the class I dehydratase MadB

An in vitro set‐up to study Pdr5‐mediated substrate translocation

A step forward to the optimized HlyA type 1 secretion system through directed evolution

Interaction of RTX toxins with the host cell plasma membrane

Waste or die: The price to pay to stay alive

Probing macromolecular crowding at the lipid membrane interface with genetically‐encoded sensors

Flipping and other astonishing transporter dance moves in fungal drug resistance

A MademoiseLLE domain binding platform links the key RNA transporter to endosomes

Optimized Hemolysin Type 1 Secretion System in Escherichia coli by Directed Evolution of the Hly Enhancer Fragment and Including a Terminator Region

Quantification and Surface Localization of the Hemolysin A Type I Secretion System at the Endogenous Level and under Conditions of Overexpression

Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5

The many facets of bile acids in the physiology and pathophysiology of the human liver

Importance of the leader peptide sequence on the lanthipeptide secretion level

Collaborators (5)

Andrzej Harris

Ulrich Schwaneberg

Michael Feldbrügge

Mehdi D. Davari

Ben Luisi

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