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Lydia Teboul

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Mary Lyon Centre at MRC Harwell

United Kingdom

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Recent Grants

Grant: Close

TransNAT: Transforming delivery, safety and efficacy of nucleic acid therapeutics: from intracellular uptake to targeting brain and muscle.

Open Date: 2022-11-01

Close Date: 2025-10-31

Grant: Open

Mary Lyon Centre - Technical Development

Open Date: 2022-03-31

Close Date: 2027-03-30

Grant: Open

Mary Lyon Centre Community Programmes - Genome Editing Mice for Medicine and the National Archive

Open Date: 2022-03-31

Close Date: 2027-03-30

Articles (19)

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Collaborators (24)

Fatima Bosch

Catedrática de Universidad

Universitat Autònoma de Barcelona (UAB)

SPAIN

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LUCILE HOUYEL

Associate Professor

Hôpital universitaire Necker-Enfants malades

FRANCE

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Matthew Butler

Academic , Consultant Senior Lecturer & MRC Clinician Scientist

University of Bristol

UNITED KINGDOM

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Richard Coward

University of Bristol

UNITED KINGDOM

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Kate Lines

University of Oxford

UNITED KINGDOM

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Joel Schick

Group Leader

Helmholtz Zentrum München Deutsches Forschungszentrum für Umwelt und Gesundheit

GERMANY

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Hannah Faith Dewhurst

Graduate Teaching Assistant

Imperial College London

UNITED KINGDOM

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Michael Piper

University of Queensland

AUSTRALIA

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Cynthia Smith

Research Scientist

Jackson Laboratory

UNITED STATES

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Marina Hughes

Honorary Senior Lecturer

Monash University Malaysia.

AUSTRALIA

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Gemma Codner

University of Oxford

UNITED KINGDOM

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Xuyu Qian

Assistant Professor

Hospital of the University of Pennsylvania

UNITED STATES

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Kelly A. Smith

University of Queensland

AUSTRALIA

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Janet Song

Assistant Professor

Harvard University

UNITED STATES

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David Adams

Senior Group Leader (and Interim Programme Head)

Wellcome Sanger Institute

UNITED KINGDOM

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Jason D. Heaney

Associate Professor (with tenure)

Baylor College of Medicine

UNITED STATES

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Tonia Vincent

Professor of Musculoskeletal Biology

University of Oxford

UNITED KINGDOM

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Guillaume Pavlovic

Head of Unit, Genetic Engineering and Model Validation

Institut Clinique de la Souris - ICS - IGBMC - CELPHEDIA

FRANCE

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Deborah Henderson

Professor of Cardiac Development

Newcastle University

UNITED KINGDOM

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James M. Amos-Landgraf

University of Missouri School of Medicine

UNITED STATES

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Louise Reynard

Senior Lecturer

Newcastle University

UNITED KINGDOM

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Cheryl Ackert-Bicknell

Associate Professor

University of Colorado Hospital

UNITED STATES

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Fabien Delerue

Macquarie University

AUSTRALIA

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Christopher Walsh

Chief

Boston Children's Hospital

UNITED STATES

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Lydia Teboul

Research Interests

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Recent Grants

Articles (19)

Multiplexed Digital PCR for Evaluation of Karyotype Quality of Mouse Embryonic Stem Cells

An ultra-conserved poison exon in the Tra2b gene encoding a splicing activator is essential for male fertility and meiotic cell division

Ocular Phenotyping of Knockout Mice Identifies Genes Associated With Late Adult Retinal Phenotypes

Better understanding of laboratory animal genetics will improve reproducibility

Parent-of-origin of alleles: an essential variable in in vivo experiments: Genetics

The splicing factor kinase SRPK1 is a therapeutic target for peripheral vascular disease

Improving laboratory animal genetic reporting: LAG-R guidelines

Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines

Beyond genomic studies of congenital heart defects through systematic modelling and phenotyping

Long-read sequencing for fast and robust identification of correct genome-edited alleles: PCR-based and Cas9 capture methods

Identification of cellular retinoic acid binding protein 2 (CRABP2) as downstream target of nuclear factor I/X (NFIX): implications for skeletal dysplasia syndromes

A Mouse Model with a Frameshift Mutation in the Nuclear Factor I/X (NFIX) Gene Has Phenotypic Features of Marshall‐Smith Syndrome

TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system

Shiga toxin targets the podocyte causing hemolytic uremic syndrome through endothelial complement activation

Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.

How much do we know about the function of mammalian genes?

Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout

Excess of guide RNA reduces knockin efficiency and drastically increases on-target large deletions

Genotyping Genome-Edited Founders and Subsequent Generation

Collaborators (24)

Fatima Bosch

LUCILE HOUYEL

Matthew Butler

Richard Coward

Kate Lines

Joel Schick

Hannah Faith Dewhurst

Michael Piper

Cynthia Smith

Marina Hughes

Gemma Codner

Xuyu Qian

Kelly A. Smith

Janet Song

David Adams

Jason D. Heaney

Tonia Vincent

Guillaume Pavlovic

Deborah Henderson

James M. Amos-Landgraf

Louise Reynard

Cheryl Ackert-Bicknell

Fabien Delerue

Christopher Walsh

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