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Lynette Ochola-Oyier

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Head of Department

KEMRI-Wellcome Trust Research Programme

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Research Interests

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Professors in Epidemiology

Recent Grants

Grant: Open

Cross-AAPs acceleration of genomics for escalating infectious diseases

Open Date: 2025-01-01

Close Date: 2027-12-31

Grant: Close

Platform for rapid immunological characterization of SARS CoV-2 variants in Kenya and the Eastern Africa Region

Open Date: 2023-01-03

Close Date: 2026-01-02

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Collaborators (15)

Collins Okoyo

Principal Statistician

Kenya Medical Research Institute

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Daniel Wright

University of Oxford

UNITED KINGDOM

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Kevin Wamae

KEMRI-Wellcome Trust Research Programme

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Charles Nyaigoti Agoti

Principal Investigator/ Group Leader

KEMRI-Wellcome Trust Research Programme

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Amy Boyd

University of Oxford

UNITED KINGDOM

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Karen I Barnes

Professor of Clinical Pharmacology

University of Cape Town

SOUTH AFRICA

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Edward Holmes

Professor

University of Sydney

AUSTRALIA

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Nyaguara Amek

Head of Surveillance

KEMRI-Wellcome Trust Research Programme

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Philip Bejon

Director MMM Unit

University of Oxford

UNITED KINGDOM

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Leonard Ndwiga

University of Glasgow

UNITED KINGDOM

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George Githinji

Bioinformatics Lead

KEMRI-Wellcome Trust Research Programme

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Alena Pance

Senior Lecturer

University of Hertfordshire

UNITED KINGDOM

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James Nyagwange

Mid-career researcher

KEMRI-Wellcome Trust Research Programme

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Paul Gichuki

Researcher

Kenya Medical Research Institute

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Alison Kemp

University of Cambridge

UNITED KINGDOM

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Lynette Ochola-Oyier

Research Interests

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Recent Grants

Articles (20)

Regional action needed to halt antimalarial drug resistance in Africa

Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya

Identification of coxsackievirus A24 variant during an acute hemorrhagic conjunctivitis outbreak in coastal Kenya, 2024 [version 2; peer review: 4 approved with reservations]

Rethinking the evidence on COVID-19 in Africa.

A retrospective analysis of P. falciparum drug resistance markers detects an early (2016/17) high prevalence of the k13 C469Y mutation in asymptomatic infections in Northern Uganda

The mRNA content of plasma extracellular vesicles provides a window into molecular processes in the brain during cerebral malaria

Kinetics of naturally induced binding and neutralising anti-SARS-CoV-2 antibody levels and potencies among SARS-CoV-2 infected Kenyans with diverse grades of COVID-19 severity: an observational study

Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in Kenya

ONT sequencing identifies a high prevalence of <i>crt</i> sensitive, triple mutant <i>dhfr</i> and single mutant <i>dhps</i> parasites within an ANC population in Nigeria.

A cross-sectional analysis identifies a low prevalence of <i>Plasmodium ovale</i> species <i> </i>infections in symptomatic and asymptomatic individuals in Kilifi county, Kenya.

Editorial: Malaria molecular epidemiology current situation in Africa

Safety and efficacy of malaria vaccine candidate R21/Matrix-M in African children: a multicentre, double-blind, randomised, phase 3 trial

Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected.

Extracellular vesicles could be a putative posttranscriptional regulatory mechanism that shapes intracellular RNA levels in Plasmodium falciparum

Low frequency of <i>Plasmodium falciparum hrp2/3</i> deletions from symptomatic infections at a primary healthcare facility in Kilifi, Kenya.

Safety and immunogenicity of ChAdOx1 nCoV-19 (AZD1222) vaccine in adults in Kenya: a phase 1/2 single-blind, randomised controlled trial

SARS-CoV-2 seroprevalence and implications for population immunity: Evidence from two Health and Demographic Surveillance System sites in Kenya, February-December 2022

Symptom prevalence and secondary attack rate of SARS-CoV-2 in rural Kenyan households: A prospective cohort study

New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March-May 2023.

Validation of saline, PBS and a locally produced VTM at varying storage conditions to detect the SARS-CoV-2 virus by qRT-PCR.

Collaborators (15)

Collins Okoyo

Daniel Wright

Kevin Wamae

Charles Nyaigoti Agoti

Amy Boyd

Karen I Barnes

Edward Holmes

Nyaguara Amek

Philip Bejon

Leonard Ndwiga

George Githinji

Alena Pance

James Nyagwange

Paul Gichuki

Alison Kemp

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