Maité Sylla

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Full Professor

Conservatoire National des Arts et Métiers

France

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Maité Sylla is a Full Professor at Conservatoire National des Arts et Metiers in France. Her research primarily focuses on the synthesis and analysis of novel compounds with potential applications in anticancer therapies, particularly targeting colorectal cancer. Recent publications include investigations into pyridyl macrocyclic triarylmethanes and their derivatives, as well as studies on coumarin derivatives and their effects on inflammation.

Recent Grants

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Etude in silico, synthèse et évaluation biologique de nouvelles molécules coumariniques : de l'activité antioxydante jusqu'à la thérapie anticancéreuse

Open Date: 2021-01-01

Close Date: 2022-12-01

Grant: Close

Synthèse de nouveaux dérivés coumariniques et évaluation de leur pouvoir antiangiogénique

Open Date: 2020-01-01

Close Date: 2021-01-01

Grant: Close

Développement de nouvelles molécules antibactériennes: repositionnement, pharmacomodulation, synthèse et études biologiques

Open Date: 2017-01-01

Close Date: 2019-01-01

Grant: Close

THERANALPHA – Theranostic small molecule TNF inhibitors

Open Date: 2017-01-01

Close Date: 2020-01-01

Grant: Close

Produits naturels de type coumarine et terpénoïdes extraits de plantes cubaines : Isolement, caractérisation analytique, synthèse et activité anti-inflammatoire

Open Date: 2017-01-01

Close Date: 2017-01-01

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2020

Collaborators (4)

RM Giner

Professor

University of Valencia

SPAIN

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Bertrand Liagre

Professor of Biochemistry and Molecular Biology

Université de Limoges

FRANCE

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Manuela Wexler

Karlsruhe Institute of Technology

GERMANY

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Sonja Mülhopt

Head of Working group Air Liquid Exposure Systems

Karlsruhe Institute of Technology

GERMANY

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Maité Sylla

Research Interests

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About

Recent Grants

Articles (16)

Fishing antioxidant 4-hydroxycoumarin derivatives: synthesis, characterization, and in vitro assessments

Novel Pyridyl Macrocyclic Triarylmethanes: Synthesis by Ring-closing Metathesis and Chemical Analysis

Colorectal anticancer activity of a novel class of triazolic triarylmethane derivatives

Anticancer effect of new cyclocoumarol derivatives

A Promising Approach to Target Colorectal Cancer Using Hybrid Triarylmethanes.

Colorectal anticancer activity of a novel class of triazolic triarylmethane derivatives.

Novel Set of Diarylmethanes to Target Colorectal Cancer: Synthesis, In Vitro and In Silico Studies

Coumarins derivatives and inflammation: Review of their effects on the inflammatory signaling pathways

Plant Occurring Flavonoids as Modulators of the Aryl Hydrocarbon Receptor

Data of the quantification of the influence of DMSO concentration on the kinetic of interaction between TNFα and SPD304

New contributions to the drug profile of TNFα inhibitor SPD304: Affinity, selectivity and ADMET considerations

Discovery of 2-aryl and 2-pyridinylbenzothiazoles endowed with antimicrobial and aryl hydrocarbon receptor agonistic activities

Predictive modeling of aryl hydrocarbon receptor (AhR) agonism

Pegylated triarylmethanes: Synthesis, antimicrobial activity, anti-proliferative behavior and in silico studies

Abstracts of the 86th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) With contribution of the Arbeitsgemeinschaft für Angewandte Humanpharmakologie e. V. (AGAH)

Targeting the aryl hydrocarbon receptor with a novel set of triarylmethanes

Collaborators (4)

RM Giner

Bertrand Liagre

Manuela Wexler

Sonja Mülhopt

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