Malcolm Low

Professor

University of Michigan

United States

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Professor Malcolm Low is a faculty member at the University of Michigan, USA. His research primarily focuses on the regulation of hypothalamic functions related to energy homeostasis and weight management. Recent articles authored by Professor Low explore the roles of various transcription factors and neuropeptides in controlling appetite and metabolic processes in animal models.

Articles (12)

Year:

2024

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2024

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2020

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2020

Year:

2020

Collaborators (3)

Elisa Na

Assistant Professor

Texas Woman's University

UNITED STATES

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Iris Lindberg

Professor

University of Maryland

UNITED STATES

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Peter Arvan

UNITED STATES

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Malcolm Low

Research Interests

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Articles (12)

The homeodomain transcription factor Six3 regulates hypothalamic Pomc expression and its absence from POMC neurons induces hyperphagia and mild obesity in male mice

A mammalian tripartite enhancer cluster controls hypothalamic Pomc expression, food intake, and body weight

Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food

The G209R mutant mouse as a model for human PCSK1 polyendocrinopathy

Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes

Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency

Regulation of Opioid Receptors by Their Endogenous Opioid Peptides

Rax Expression Identifies a Novel Cell Type in the Adult Mouse Hypothalamus

Mice lacking PC1/3 expression in POMC-expressing cells do not develop obesity

Decreased sensitivity to the anorectic effects of leptin in mice that lack a Pomc-specific neural enhancer

MON-709 Single-Cell RNA-Sequencing Deciphers POMC Neuron Destiny

OR16-03 Metabolic Effects Of Hypothalamic Pomc Neurons Generated Postnatally From Tanycytes On A Pomc Null Genetic Background

Collaborators (3)

Elisa Na

Iris Lindberg

Peter Arvan

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