Manali Mukherjee

Assistant Professor

McMaster University

Canada

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About

Dr. Manali Mukherjee is an Assistant Professor at McMaster University in Canada. Her research focuses on severe asthma, including investigations into treatment responses and immune mechanisms. Recent publications explore topics such as the endotypic classification of asthma and the effects of biologics on sputum eosinophilia. She is also involved in research examining barriers to multisite studies within the context of COVID-19.

Articles (18)

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2025

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2022

Collaborators (10)

Ellen Tufvesson

SWEDEN

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Anna Sediva

vice-head

University Hospital in Motol

CZECH REPUBLIC

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Paige Lacy

Professor

University of Alberta

CANADA

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Martin Kolb

Professor

McMaster University Faculty of Health Sciences

CANADA

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Hana Serajeddini

Clinician Researcher, Assistant Professor of Medicine, Consultant Respirologist

Western University

CANADA

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Pat Camp

Associate Professor / Dr.

The University of British Columbia

CANADA

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Leo Koenderman

NETHERLANDS

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Parameswaran Nair

CANADA

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Zuzana Diamant

Guest Professor

Catholic University of Leuven

BELGIUM

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Sven Seys

Chief Scientific Officer

Hippo Dx

BELGIUM

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Manali Mukherjee

Research Interests

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Articles (18)

Neutrophilic asthma may not be a distinct endotype

Computational fluid dynamics model predictions of inhaled corticosteroid deposition in patients with severe asthma

Up‐dosing of reslizumab in severe asthmatics with persistent sputum eosinophilia: A feasibility study

Trajectories of responses to mepolizumab in severe asthma

Response of sputum periostin to anti‐T2 biologics treatment in severe asthma

Barriers to multisite research in Canada: Experiences from a minimal risk COVID-19 study

Sputum cytokines associated with raised FeNO after anti‐IL5 biologic therapy in severe asthma

Eosinophils—from cradle to grave

A novel take on idiopathic pulmonary fibrosis disease progression: localised autoimmunity

Benralizumab Normalizes Sputum Eosinophilia in Severe Asthma Uncontrolled by Anti–IL-5 Antibodies: A Single-Blind, Placebo-controlled Clinical Trial

A sputum bioassay for airway eosinophilia using an eosinophil peroxidase aptamer.

Airway autoantibodies are determinants of asthma severity.

Airway autoimmunity, asthma exacerbations, and response to biologics

A Unique CD27-IgD- B Cell Population in the Sputum of Severe Eosinophilic Asthma Associated with Airway Autoimmunity

A case series of dual biologics therapy for severe asthma.

Autoantibody-mediated Macrophage Dysfunction in Severe Asthma Patients with Airway Infections.

Impact of former smoking exposure on airway eosinophilic activation and autoimmunity in patients with severe asthma

Benralizumab's anti-eosinophil efficacy may be decreased by impaired NK cell activity

Collaborators (10)

Ellen Tufvesson

Anna Sediva

Paige Lacy

Martin Kolb

Hana Serajeddini

Pat Camp

Leo Koenderman

Parameswaran Nair

Zuzana Diamant

Sven Seys

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