Manoj Kumar Pandey

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Faculty-Assistant Professor and Principal Investigator

Cincinnati Children's Hospital Medical Center

United States

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About

Dr. Manoj Kumar Pandey is an Assistant Professor and Principal Investigator at Cincinnati Children's Hospital Medical Center, USA. His research focuses on the complement system's role in neuroinflammation, lymphocyte complement initiation, and lipid diplomacy in disease mechanisms. He also investigates the pathogenesis of metabolic disorders and contributes to advances in molecular classification and pharmaceutical microbiology.

Recent Grants

Grant: Close

Complement 5a mediated innate immunity in neurofibroma formation

Open Date: 2019-07-01

Close Date: 2020-06-01

Grant: Close

Targeting complement 5a-mediated immunoregulation for neurofibroma therapy

Open Date: 2019-07-01

Close Date: 2021-08-01

Grant: Close

GBA1 defects cause C5a-C5aR1-induced neurodegeneration in Parkinson’s disease

Open Date: 2018-12-01

Close Date: 2020-12-01

Grant: Close

C5a-C5aR1 function for brain storage of glucosylceramide in Gaucher disease.

Open Date: 2017-08-01

Close Date: 2018-06-01

Grant: Close

Complement drives neurodegeneration in Gaucher disease. The goal of this study is to define new mechanisms by which C5a and its receptor C5aR1 drive neurodegeneration in Gaucher disease

Open Date: 2017-07-01

Close Date: 2019-06-01

Articles (20)

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2021

Collaborators (2)

Luca Marsili

University of Cincinnati

UNITED STATES

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Joerg Koehl

Director and Professor of Immunology

University of Lübeck

GERMANY

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Manoj Kumar Pandey

Research Interests

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About

Recent Grants

Articles (20)

Emerging role of complement system in the induction of neuroinflammation in adenylosuccinate lyase deficiency disorder.

A new member at the table: Granzyme K as a lymphocyte‐born complement initiator

Molecular Diplomacy of Lipids in the War of Immunity: Bridging Rare and Common Disease Mechanisms

A zebrafish model of <i>crim1</i> loss of function has small and misshapen lenses with dysregulated <i>clic4</i> and <i>fgf1b</i> expression.

Complement Inhibition Expands the Therapeutic Window of Amyloid-β Immunotherapy in Alzheimer's Disease

Complement System and Adhesion Molecule Skirmishes in Fabry Disease: Insights into Pathogenesis and Disease Mechanisms

Amyloidogenic Propensity of Metabolites in the Uric Acid Pathway and Urea Cycle Critically Impacts the Etiology of Metabolic Disorders

Computational Approach to Elucidating Insulin-Protamine Binding Interactions and Dynamics in Insulin NPH Formulations

Editorial: Advances in molecular classification and targeting of solid tumors

Engineering advances in safe laboratory design for pharmaceutical microbiology and assessment of their biohazard risk measures

Uncovering the Lipid Web: Discovering the Multifaceted Roles of Lipids in Human Diseases and Therapeutic Opportunities

Exploring Pro-Inflammatory Immunological Mediators: Unraveling the Mechanisms of Neuroinflammation in Lysosomal Storage Diseases

Targeting the Complement–Sphingolipid System in COVID-19 and Gaucher Diseases: Evidence for a New Treatment Strategy

Fat and Protein Combat Triggers Immunological Weapons of Innate and Adaptive Immune Systems to Launch Neuroinflammation in Parkinson's Disease.

Pre‐existing humoral immune comebacks control the development of the severe form of coronavirus disease 2019 in Gaucher patients

The Role of Alpha-Synuclein Autoantibodies in the Induction of Brain Inflammation and Neurodegeneration in Aged Humans

C-X-C Motif Chemokine Ligand 9 and Its CXCR3 Receptor Are the Salt and Pepper for T Cells Trafficking in a Mouse Model of Gaucher Disease

Genetic Defects and Pro-inflammatory Cytokines in Parkinson's Disease

Genetic parkinsonisms and cancer: a systematic review and meta-analysis

C-X-C Motif Chemokine Ligand 9 and Its CXCR3 Receptor Are the Salt and Pepper for T Cells Trafficking in a Mouse Model of Gaucher Disease

Collaborators (2)

Luca Marsili

Joerg Koehl

Make your next move.

Manoj Kumar Pandey

Research Interests

Explore related searches

Contact this professor

About

Recent Grants

Articles (20)

Emerging role of complement system in the induction of neuroinflammation in adenylosuccinate lyase deficiency disorder.

A new member at the table: Granzyme K as a lymphocyte‐born complement initiator

Molecular Diplomacy of Lipids in the War of Immunity: Bridging Rare and Common Disease Mechanisms

A zebrafish model of &lt;i&gt;crim1&lt;/i&gt; loss of function has small and misshapen lenses with dysregulated &lt;i&gt;clic4&lt;/i&gt; and &lt;i&gt;fgf1b&lt;/i&gt; expression.

Complement Inhibition Expands the Therapeutic Window of Amyloid-β Immunotherapy in Alzheimer's Disease

Complement System and Adhesion Molecule Skirmishes in Fabry Disease: Insights into Pathogenesis and Disease Mechanisms

Amyloidogenic Propensity of Metabolites in the Uric Acid Pathway and Urea Cycle Critically Impacts the Etiology of Metabolic Disorders

Computational Approach to Elucidating Insulin-Protamine Binding Interactions and Dynamics in Insulin NPH Formulations

Editorial: Advances in molecular classification and targeting of solid tumors

Engineering advances in safe laboratory design for pharmaceutical microbiology and assessment of their biohazard risk measures

Uncovering the Lipid Web: Discovering the Multifaceted Roles of Lipids in Human Diseases and Therapeutic Opportunities

Exploring Pro-Inflammatory Immunological Mediators: Unraveling the Mechanisms of Neuroinflammation in Lysosomal Storage Diseases

Targeting the Complement–Sphingolipid System in COVID-19 and Gaucher Diseases: Evidence for a New Treatment Strategy

Fat and Protein Combat Triggers Immunological Weapons of Innate and Adaptive Immune Systems to Launch Neuroinflammation in Parkinson's Disease.

Pre‐existing humoral immune comebacks control the development of the severe form of coronavirus disease 2019 in Gaucher patients

The Role of Alpha-Synuclein Autoantibodies in the Induction of Brain Inflammation and Neurodegeneration in Aged Humans

C-X-C Motif Chemokine Ligand 9 and Its CXCR3 Receptor Are the Salt and Pepper for T Cells Trafficking in a Mouse Model of Gaucher Disease

Genetic Defects and Pro-inflammatory Cytokines in Parkinson's Disease

Genetic parkinsonisms and cancer: a systematic review and meta-analysis

C-X-C Motif Chemokine Ligand 9 and Its CXCR3 Receptor Are the Salt and Pepper for T Cells Trafficking in a Mouse Model of Gaucher Disease

Collaborators (2)

Luca Marsili

Joerg Koehl

Make your next move.

A zebrafish model of <i>crim1</i> loss of function has small and misshapen lenses with dysregulated <i>clic4</i> and <i>fgf1b</i> expression.