Manu Platt

Associate Professor

Georgia Institute of Technology

United States

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Dr. Manu Platt is an Associate Professor at the Georgia Institute of Technology, USA. His research focuses on the pathophysiology of sickle cell disease, enzyme kinetics, and the use of metabolomics for T-cell suppression. Recent publications have explored topics such as arterial compliance in genetically modified mice and the proteolytic activity of cysteine cathepsins in various biological contexts.

Articles (9)

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2025

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2022

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2022

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2022

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2021

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2020

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2020

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2020

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2020

Collaborators (5)

Edward A. Botchwey

UNITED STATES

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Arthur M. Mercurio

University of Massachusetts Chan Medical School

UNITED STATES

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Chris Kieslich

Assistant Professor

Auburn University

UNITED STATES

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Hannah Song Lee

National Institutes of Health

UNITED STATES

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Meghan Ferrall-Fairbanks

Assistant Professor

University of Florida

UNITED STATES

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Manu Platt

Research Interests

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Articles (9)

Bone marrow transplant protects mice from sickle cell–mediated large artery remodeling

Comparative analysis of arterial compliance in mice genetically null for cathepsins K, L, or S

Sickle cell disease promotes sex-dependent pathological bone loss through enhanced cathepsin proteolytic activity in mice

Metabolomics and cytokine profiling of mesenchymal stromal cells identify markers predictive of T-cell suppression

Multiple sites on SARS‐CoV‐2 spike protein are susceptible to proteolysis by cathepsins B, K, L, S, and V

Cysteine cathepsins are altered by flow within an engineered in vitro microvascular niche

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Tumor cell–organized fibronectin maintenance of a dormant breast cancer population

Reassessing enzyme kinetics: Considering protease-as-substrate interactions in proteolytic networks

Collaborators (5)

Edward A. Botchwey

Arthur M. Mercurio

Chris Kieslich

Hannah Song Lee

Meghan Ferrall-Fairbanks

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