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Manuel Alcalde-Rico

Has grant

Professor/Researcher

Universidad de Sevilla

Spain

Research Interests

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Recent Grants

Grant: Open

Role of mobile genetic elements in heteroresistance to novel antibiotic combinations in Pseudomonas aeruginosa isolates resistant to all conventional β-lactams

Open Date: 2026-02-01

Close Date: 2030-01-01

Grant: Open

Role of mobile genetic elements in heteroresistance to novel antibiotic combinations of Pseudomonas aeruginosa isolates resistant to all classical beta-lactams

Open Date: 2025-01-01

Close Date: 2027-12-01

Grant: Open

Role of integrases, transposases and recombinases in resistance and heteroresistance to beta-lactams in Pseudomonas aeruginosa and Klebsiella pneumoniae producing ESBLs and/or carbapenemases. InTraRec Project

Open Date: 2024-01-01

Close Date: 2028-12-01

Grant: Close

Characterization of the activity of two new antibiotics against non-carbapenemase producing, carbapenem-resistant P. aeruginosa (non-CP-CR-PAE) and determination of the molecular mechanisms involved in their resistance

Open Date: 2021-06-01

Close Date: 2022-06-01

Grant: Close

Molecular and epidemiological characterization of multidrug-resistant clinical isolates of Pseudomonas aeruginosa from Chilean hospitals and analysis of the role of high-risk clones in the prevalence and dispersion of carbapenemases

Open Date: 2020-04-01

Close Date: 2023-04-01

Articles (15)

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Collaborators (7)

Søren Molin

Technical University of Denmark

DENMARK

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Jesús Rodríguez-Baño

Professor

Universidad de Sevilla

SPAIN

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Signe Lolle

Technical University of Denmark

DENMARK

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Sara M. Soto

Associate Research Professor

Instituto de Salud Global Barcelona

SPAIN

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Stephanie Egge

Assistant Professor

Oregon Health & Science University

UNITED STATES

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Mª Carmen Conejo Gonzalo

Profesor Titular de Universidad

Universidad de Sevilla

SPAIN

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Sara Marti

Group Leader (Translational Medicine Area)

Institut d'Investigacio Biomedica de Bellvitge (IDIBELL)

SPAIN

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Manuel Alcalde-Rico

Research Interests

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Recent Grants

Articles (15)

A matched case-control study on Escherichia coli factors contributing to sepsis and septic shock in bacteraemic patients

Antibiotic use in Chilean salmon aquaculture: antimicrobial resistance, sustainability, and One Health implications

Emergence and persistence of ESBL- and carbapenemase-producing <i>Klebsiella pneumoniae</i>-related species in Barcelona wastewater treatment plants

Integrated metagenomic, culture-based, and whole genome sequencing analyses of antimicrobial resistance in wastewater and drinking water treatment plants in Barcelona, Spain

Biocide exposure in extended-spectrum β-lactamase-producing Klebsiella pneumoniae: effect on increased biocide and antibiotic MICs, genetic changes, and fitness cost

<i>Pseudomonas gelidaquae</i> sp. nov., an Antarctic bacterium with a distinctive Type III Secretion System, isolated from Fildes Bay, King George Island

Geographic divergence of methicillin-resistant <i>Staphylococcus aureus</i> ST5-SCC<i>mec</i>I in the aftermath of a major earthquake and tsunami: impact of a plasmid harboring heavy metal resistance genes

Gut dysbiosis after successive administration of florfenicol-medicated feed alters intestinal inflammatory response and growth patterns in healthy Atlantic salmon (<i>Salmo salar</i>)

Activity of imipenem/relebactam and comparators against KPC-producing Klebsiella pneumoniae and imipenem-resistant Pseudomonas aeruginosa

Cefiderocol heteroresistance associated with mutations in TonB-dependent receptor genes in <i>Pseudomonas aeruginosa</i> of clinical origin

Mutations in the efflux pump regulator MexZ shift tissue colonization by Pseudomonas aeruginosa to a state of antibiotic tolerance

A whole-cell hypersensitive biosensor for beta-lactams based on the AmpR-AmpC regulatory circuit from the Antarctic <i>Pseudomonas</i> sp. IB20

Ceftazidime/avibactam resistance is associated with PER-3-producing ST309 lineage in Chilean clinical isolates of non-carbapenemase producing <i>Pseudomonas aeruginosa</i>

Dynamics of the MRSA Population in a Chilean Hospital: a Phylogenomic Analysis (2000–2016)

Efflux pump mutations in<italic> Pseudomonas aeruginosa</italic> cause low-level clinical resistance and high-level tolerance to antibiotics in patients

Collaborators (7)

Søren Molin

Jesús Rodríguez-Baño

Signe Lolle

Sara M. Soto

Stephanie Egge

Mª Carmen Conejo Gonzalo

Sara Marti

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