Manuel Portoles

PROFESOR ASOCIADO

University of Valencia

Spain

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Professor Manuel Portoles is an Associate Professor at the Universitat de València, Spain. His research focuses on the molecular mechanisms underlying cardiovascular diseases, including heart transplant rejection and heart failure. Recent publications highlight his work on circulating piRNAs, alternative splicing factors, and the role of sodium-glucose co-transporters in inflammation-related processes.

Articles (13)

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2025

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2024

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2024

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2021

Collaborators (2)

María Dolores García Manzanares

Universidad CEU Cardenal Herrera

SPAIN

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Esther Roselló-Lletí

SPAIN

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Manuel Portoles

Research Interests

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Articles (13)

Emerging role of circulating piRNAs in the diagnosis of heart transplant rejection

Transcriptomic Alterations in Spliceosome Components in Advanced Heart Failure: Status of Cardiac-Specific Alternative Splicing Factors

Alterations in Mitochondrial Oxidative Phosphorylation System: Relationship of Complex V and Cardiac Dysfunction in Human Heart Failure

Altered MicroRNA Maturation in Ischemic Hearts: Implication of Hypoxia on XPO5 and DICER1 Dysregulation and RedoximiR State

Cardiac Sodium/Hydrogen Exchanger (NHE11) as a Novel Potential Target for SGLT2i in Heart Failure: A Preliminary Study

Relaxin-2 as a Potential Biomarker in Cardiovascular Diseases

Cardiac Allograft Rejection Induces Changes in Nucleocytoplasmic Transport: RANGAP1 as a Potential Non-Invasive Biomarker

Role of Sodium-Glucose Co-Transporter 2 Inhibitors in the Regulation of Inflammatory Processes in Animal Models

DNMT3B System Dysregulation Contributes to the Hypomethylated State in Ischaemic Human Hearts

Electron Microscopy Reveals Evidence of Perinuclear Clustering of Mitochondria in Cardiac Biopsy-Proven Allograft Rejection

Diagnostic value of serum miR-144-3p for the detection of acute cellular rejection in heart transplant patients

Implication of Sphingolipid Metabolism Gene Dysregulation and Cardiac Sphingosine-1-Phosphate Accumulation in Heart Failure

Relationships of Telomere Homeostasis with Oxidative Stress and Cardiac Dysfunction in Human Ischaemic Hearts

Collaborators (2)

María Dolores García Manzanares

Esther Roselló-Lletí

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