Manuela Tosin

department of chemistry university of york heslington

United Kingdom

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Articles (9)

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

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2023

Year:

2023

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2021

Year:

2021

Collaborators (5)

Gregory Challis

Monash Warwick Alliance Professor of Sustainable Chemistry (Chemical and Synthetic Biology)

MONASH UNIVERSITY

AUSTRALIA

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Max J. Cryle

MONASH UNIVERSITY

AUSTRALIA

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Joe A. Kaczmarski

AUSTRALIA

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Christophe Corre

Professor in Engineering Biology

University of Warwick

UNITED KINGDOM

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Fabrizio Alberti

UKRI Future Leaders Fellow (Associate Professor)

University of Warwick

UNITED KINGDOM

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Manuela Tosin

Research Interests

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Articles (9)

How to Find a Fragment: Methods for Screening and Validation in Fragment‐Based Drug Discovery

Extended polyene formation by a cryptic iterative polyketide synthase from Rhodococcus

P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate

Not always an innocent bystander: the impact of stabilised phosphopantetheine moieties when studying nonribosomal peptide biosynthesis

Exploring the selectivity and engineering potential of an NRPS condensation domain involved in the biosynthesis of the thermophilic siderophore fuscachelin

Crystal structure of dihydrofolate reductase from the emerging pathogenic fungus <i>Candida auris</i>

Fragment‐Merging Strategies with Known Pyrimidine Scaffolds Targeting Dihydrofolate Reductase from <i>Mycobacterium tuberculosis</i>

Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity

Chemical probes reveal the timing of early chlorination in vancomycin biosynthesis

Collaborators (5)

Gregory Challis

Max J. Cryle

Joe A. Kaczmarski

Christophe Corre

Fabrizio Alberti

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