Maolin Lu

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Assistant Professor

The University of Texas Health Science Center at Tyler

United States

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About

Maolin Lu is an Assistant Professor at the University of Texas Health Science Center at Tyler. His research focuses on the structural biology and mechanisms of viral infections, particularly related to HIV-1 and SARS-CoV-2. Recent publications highlight his work on viral envelope dynamics, antibody responses, and the impact of viral variants on cell entry and immune evasion.

Recent Grants

Grant: Close

HIV-1 fusion studied by parallel single-molecule FRET and cryo-electron tomography

Open Date: 2021-07-01

Close Date:

Grant: Close

HIV-1 fusion studied by parallel single-molecule FRET and cryo-electron tomography

Open Date: 2019-10-01

Close Date: 2021-05-01

Articles (13)

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2025

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2025

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2024

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (7)

Corby Fink

Assistant Professor

University of Manitoba

CANADA

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Julia Niessl

Karolinska Institutet

SWEDEN

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Andrés Finzi

Associate Professor

Université de Montréal

CANADA

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Rory Henderson

Assistant Professor

Duke University

UNITED STATES

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Ye Zhou

Duke University

UNITED STATES

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Revansiddha Katte

The University of Texas Health Science Center at Tyler

UNITED STATES

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Priyamvada Acharya

Associate Professor

Duke University

UNITED STATES

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Maolin Lu

Research Interests

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Contact this professor

About

Recent Grants

Articles (13)

Inter-protomer opening cooperativity of envelope trimers positively correlates with HIV-1 entry stoichiometry

Protocol for click labeling of HIV-1 envelope on amber-free virions prepared using genetic code expansion

Differentiating Cell Entry Potentials of SARS-CoV-2 Omicron Subvariants on Human Lung Epithelium Cells

Structural Plasticity and Immune Evasion of SARS-CoV-2 Spike Variants

SARS-CoV-2 Variants Increase Kinetic Stability of Open Spike Conformations as an Evolutionary Strategy

Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern

A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses

Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer

Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy

Single-Molecule FRET Imaging of Virus Spike-Host Interactions.

Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements

Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles.

Correction for Lu et al., “Shedding-Resistant HIV-1 Envelope Glycoproteins Adopt Downstream Conformations That Remain Responsive to Conformation-Preferring Ligands”

Collaborators (7)

Corby Fink

Julia Niessl

Andrés Finzi

Rory Henderson

Ye Zhou

Revansiddha Katte

Priyamvada Acharya

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