Marc Bitoun

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INSERM

France

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Role of dynamin 2 in muscle under normal and pathological conditions – Dynamuscle

Open Date: 2014-09-20

Close Date: 2017-09-19

Grant: Close

Therapy by modulation of Dynamin 2 expression – DynaTher

Open Date:

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Articles (11)

Year:

2023

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2020

Collaborators (4)

Belinda Cowling

VP, Head of Biomarkers

Vertex Pharmaceuticals (United States)

UNITED STATES

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Delphine Trochet

FRANCE

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Sofia Benkhelifa-Ziyyat

PhD, Senior Researcher, Head of MyoVector platform

Institut de Myologie

FRANCE

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Christophe Leterrier

FRANCE

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Marc Bitoun

Research Interests

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Recent Grants

Articles (11)

A centronuclear myopathy-causing mutation in dynamin-2 disrupts neuronal morphology and excitatory synaptic transmission in a murine model of the disease.

Caveolae and Bin1 form ring-shaped platforms for T-tubule initiation

La myopathie centronucléaire liée au gène de la dynamine 2

Benefits of therapy by dynamin-2-mutant-specific silencing are maintained with time in a mouse model of dominant centronuclear myopathy

Development of versatile allele-specific siRNAs able to silence all the dominant dynamin 2 mutations

Muscle regeneration affects Adeno Associated Virus 1 mediated transgene transcription.

BIN1 modulation in vivo rescues dynamin-related myopathy

A review of Dynamin 2 involvement in cancers highlights a promising therapeutic target

Comment l’épissage alternatif contribue au contrôle de la plasticité des structures de clathrine

Satellite cells deficiency and defective regeneration in dynamin 2‐related centronuclear myopathy

Alternative splicing of clathrin heavy chain contributes to the switch from coated pits to plaques.

Collaborators (4)

Belinda Cowling

Delphine Trochet

Sofia Benkhelifa-Ziyyat

Christophe Leterrier

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