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Marcello D'Amelio

Full Professor, Human Physiology

Campus Bio Medico University Hospital

Italy

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Research Interests

Pharmacology

20%

Systems Neuroscience

20%

Neuroprotection

60%

Neuropharmacology

40%

Neuroplasticity

30%

Proteostasis

30%

Anti-aging Research

20%

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Articles18

Reconsidering dopaminergic modulation in Alzheimer's disease: A case for levodopa/carbidopa as a disease‐modifying agent

Article Link

Year:

2025

Chemogenetic induction of CA1 hyperexcitability triggers indistinguishable autistic traits in asymptomatic mice differing in Ambra1 expression and sex

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Year:

2025

Disarming COX-1 to disrupt Alzheimer’s inflammatory trajectory: preclinical insights and translational promise

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Year:

2025

A spit for a tip in dementia diagnosis: Evidence from saliva for dementia with Lewy bodies

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Year:

2025

Dopamine neuron degeneration in the Ventral Tegmental Area causes hippocampal hyperexcitability in experimental Alzheimer’s Disease

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Year:

2024

Transcranial alternating current stimulation (tACS) at gamma frequency: an up-and-coming tool to modify the progression of Alzheimer’s Disease

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Year:

2024

Clarifying the role of D1 receptor signalling in Alzheimer's‐related epilepsy commentary on Szabo et al. (2024)

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Year:

2024

Chemogenetic rectification of the inhibitory tone onto hippocampal neurons reverts autistic-like traits and normalizes local expression of estrogen receptors in the Ambra1+/- mouse model of female autism

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Year:

2023

Nilotinib: from animal-based studies to clinical investigation in Alzheimer's disease patients

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Year:

2023

The role of dopamine in NLRP3 inflammasome inhibition: Implications for neurodegenerative diseases

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Year:

2023

Can transcranial magnetic stimulation rescue dopaminergic signalling in Alzheimer’s disease?

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Year:

2023

Correction: Cutuli et al. Neuroprotective Role of Dietary Supplementation with Omega-3 Fatty Acids in the Presence of Basal Forebrain Cholinergic Neurons Degeneration in Aged Mice (Int. J. Mol. Sci. 2020, 21, 1741)

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Year:

2022

Functionalization strategies of polymeric nanoparticles for drug delivery in Alzheimer’s disease: Current trends and future perspectives

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Year:

2022

Restoration of ER proteostasis attenuates remote apoptotic cell death after spinal cord injury by reducing autophagosome overload

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Year:

2022

The VTA dopaminergic system as diagnostic and therapeutical target for Alzheimer's disease

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Year:

2022

Upregulation of Ca<sup>2+</sup>-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer’s disease in Tg2576 mice

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Year:

2022

Early derailment of firing properties in CA1 pyramidal cells of the ventral hippocampus in an Alzheimer's disease mouse model.

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Year:

2021

In vivo human molecular neuroimaging of dopaminergic vulnerability along the Alzheimer's disease phases.

Article Link

Year:

2021

Collaborators5

MASSIMILIANO RENZI

Associate Professor

Università degli Studi di Roma La Sapienza

ITALY

Annalisa Nobili

University Campus Bio-Medico

ITALY

Paola De Bartolo

Associate Professor

Università degli Studi Guglielmo Marconi

ITALY

Rossella Ventura

Università degli Studi di Roma La Sapienza Facoltà di Medicina e Psicologia

ITALY

Stefano Sacchetti

University of Rome Tor Vergata

ITALY

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