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Marcin Kolaczkowski

Profesor nadzwyczajny/dr hab.

Uniwersytet Jagiellonski Collegium Medicum

Poland

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Research Interests

Biochemistry

10%

Pharmaceutical Chemistry

70%

Neuropharmacology

30%

Ligand Design

30%

G Protein-coupled Receptor

30%

Ligand Chemistry

30%

Chemical Biology

20%

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Articles13

Carbon Monoxide in Medicine: Emerging Therapeutic Perspectives

Article Link

Year:

2025

Targeted protein degradation via the endosome–lysosome pathway: A novel pharmacological strategy for modulating extracellular protein function

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Year:

2025

Application of automated machine learning in the identification of multi‐target‐directed ligands blocking PDE4B, PDE8A, and TRPA1 with potential use in the treatment of asthma and COPD

Article Link

Year:

2023

The use of machine learning-based sequential virtual screening in the search of new ligands of 5-HT6 receptor

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Year:

2023

2-(4-Fluorophenyl)-1H-benzo[d]imidazole as a Promising Template for the Development of Metabolically Robust, α1β2γ2GABA-A Receptor-Positive Allosteric Modulators

Article Link

Year:

2023

Neuroprotective Activity of Enantiomers of Salsolinol and N-Methyl-(R)-salsolinol: In Vitro and In Silico Studies

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Year:

2023

Spontaneous head twitches in aged rats: behavioral and molecular study

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Year:

2022

Synthesis, In Vitro, and Computational Studies of PTP1B Phosphatase Inhibitors Based on Oxovanadium(IV) and Dioxovanadium(V) Complexes

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Year:

2022

Curcumin and Its New Derivatives: Correlation between Cytotoxicity against Breast Cancer Cell Lines, Degradation of PTP1B Phosphatase and ROS Generation

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Year:

2021

Carbonyl reduction pathway in hepatic in vitro metabolism of anthracyclines: Impact of structure on biotransformation rate

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Year:

2021

Development and crystallography-aided SAR studies of multifunctional BuChE inhibitors and 5-HT<inf>6</inf>R antagonists with β-amyloid anti-aggregation properties

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Year:

2021

Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT<inf>6</inf> receptor with anti-aggregation properties against amyloid-beta and tau

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Year:

2021

Multifunctional Arylsulfone and Arylsulfonamide-Based Ligands with Prominent Mood-Modulating Activity and Benign Safety Profile, Targeting Neuropsychiatric Symptoms of Dementia

Article Link

Year:

2021

Collaborators16

Monika Marcinkowska

Assistant professor

Uniwersytet Jagiellonski Collegium Medicum

POLAND

Joanna Śniecikowska

Assistant Professor

Uniwersytet Jagiellonski Collegium Medicum

POLAND

Joanna Drzeżdżon

assistant professor

University of Gdańsk

POLAND

Alicja Gawalska

Lecturer Assistant

Uniwersytet Jagiellonski Collegium Medicum

POLAND

PAWEŁ MIERZEJEWSKI

Institute of Psychiatry and Neurology

POLAND

Alicja Kuban-Jankowska

Medical University of Gdansk

POLAND

Agnieszka Zagórska

Assistant Professor

Uniwersytet Jagiellonski Collegium Medicum

POLAND

Adam Bucki

Assistant professor

Uniwersytet Jagiellonski Collegium Medicum

POLAND

Irena Nalepa

Professor, Ph.D., Head of Department

Maj Institute of Pharmacology Polish Academy of Sciences

POLAND

Aleksander Mendyk

professor with tenure / PhD, DSc

Uniwersytet Jagiellonski Collegium Medicum

POLAND

magdalena gorska-ponikowska

Associate Professor

Medical University of Gdansk

POLAND

Julita Kuczyńska

Institute of Psychiatry and Neurology

POLAND

Dagmara Jacewicz

University of Gdańsk

POLAND

Natalia Łapińska

Jagiellonian University

POLAND

Tomasz Kostrzewa

Assistant Professor

Medical University of Gdansk

POLAND

Maria Walczak

Jagiellonian University Medical College

POLAND

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