Marcus Ladds

Karolinska Institutet

Sweden

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Professors in Sweden Professors in Cancer Biology Cancer Biology professors in Sweden

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Articles (7)

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Year:

2020

Collaborators (5)

Sonia Lain

Karolinska Institutet

SWEDEN

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Stephanie May

Honorary Lecturer

University of Glasgow

UNITED KINGDOM

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Joseph Gault

AstraZeneca UK Limited

UNITED KINGDOM

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Marie Arsenian Henriksson

Karolinska Institutet

SWEDEN

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Emmet McCormack

University of Bergen

NORWAY

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Marcus Ladds

Research Interests

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Articles (7)

Dihydroorotate dehydrogenase inhibition acts synergistically with tyrosine kinase inhibitors to induce apoptosis of mantle cell lymphoma cells

DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance

CD36 and LC3B initiated autophagy in B cells regulates the humoral immune response

Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

Combining native and ‘omics’ mass spectrometry to identify endogenous ligands bound to membrane proteins

Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability.

Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology

Collaborators (5)

Sonia Lain

Stephanie May

Joseph Gault

Marie Arsenian Henriksson

Emmet McCormack

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