Margaret Fahnestock

Professor

McMaster University

Canada

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Professor Margaret Fahnestock is a faculty member at McMaster University in Canada. Her research primarily focuses on pain management, neurobiology, and the effects of exercise on brain health, with recent articles exploring topics such as knee osteoarthritis and muscle-brain interactions in aging. She is actively involved in studies assessing the feasibility and effectiveness of novel movement programs and exercise interventions for enhancing cognitive health and mitigating neurodegeneration.

Articles (19)

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2025

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2025

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2025

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2025

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2021

Collaborators (12)

Martin Gibala

Professor

McMaster University

CANADA

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ponnambalam ravi selvaganapathy

Professor

McMaster University

CANADA

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Izabela Zaborniak

Assistant Professor

Rzeszów University

POLAND

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R. J. Rylett

CANADA

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Dawn M. E. Bowdish

McMaster University

CANADA

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Paul Forsythe

University of Alberta

CANADA

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Jennifer D Walker

Associate Professor

McMaster University

CANADA

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Kim Madden

Assistant Professor

McMaster University

CANADA

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Paweł Chmielarz

Full Professor

Rzeszów University

POLAND

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Grzegorz Bartosz

Professor

Uniwersytet Wroclawski

POLAND

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Izabela Sadowska-Bartosz

Head of Laboratory/Professor

Rzeszów University

POLAND

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Lisa Carlesso

Assistant Professor

McMaster University

CANADA

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Margaret Fahnestock

Research Interests

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About

Articles (19)

The Effects of Electrical Stimulation on a 3D Osteoblast Cell Model

Pain informed movement compared to neuromuscular exercise and standard education in people with knee osteoarthritis: A pilot and feasibility randomized controlled trial

Muscle-brain crosstalk as a driver of brain health in aging

Nutrient sensing receptor GPRC6A regulates mTORC1 signaling and Tau biology

602 FEASIBILITY AND preliminary EFFECTIVENESS OF Pain Informed Movement for KNEE OSTEOARTHRITIS: A Pilot RANDOMIZED controlled TRIAL

Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA)

Combining AlphaFold and molecular dynamics simulations to determine the complete structures of isoforms of human brain-derived neurotrophic factor and human nerve growth factor

Feasibility of pain informed movement program for people with knee osteoarthritis

Pain Informed Movement for people with knee osteoarthritis: Protocol for a pilot randomized controlled trial

Feasibility of a pain informed movement program for people with symptomatic knee osteoarthritis

The Effects of Exercise on Synaptic Plasticity in Individuals With Mild Cognitive Impairment: Protocol for a Pilot Intervention Study

Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease

Induction of Oxidative Stress in SH-SY5Y Cells by Overexpression of hTau40 and Its Mitigation by Redox-Active Nanoparticles

Rationale, methods, and progress of the ArthroCaP Study: A prospective cohort study exploring the associations between chronic postsurgical pain and postoperative cognitive dysfunction after elective knee or hip arthroplasty

Gonadal Hormones Contribute to Sex Differences in Autoimmunity, Pathology and Behaviour in the 3×Tg‐AD Mouse Model of Alzheimer’s Disease

Nurr1 Is Not an Essential Regulator of BDNF in Mouse Cortical Neurons

Sex-Dependent Differences in Serum Autoantibody Levels in the 3×Tg-AD Model of Alzheimer’s Disease

Retrograde Axonal Transport of Neurotrophins in Basal Forebrain Cholinergic Neurons

Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer's disease-associated markers in 3xTg-AD mice.

Collaborators (12)

Martin Gibala

ponnambalam ravi selvaganapathy

Izabela Zaborniak

R. J. Rylett

Dawn M. E. Bowdish

Paul Forsythe

Jennifer D Walker

Kim Madden

Paweł Chmielarz

Grzegorz Bartosz

Izabela Sadowska-Bartosz

Lisa Carlesso

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