Marianne Sadar

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Full Professor (current rank)

The University of British Columbia

Canada

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Recent Grants

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Structure, function, and application of novel antagonists of the intrinsically disordered androgen receptor amino-terminal domain as imaging agents and therapeutics

Open Date: 2021-01-01

Close Date: 2026-01-01

Grant: Close

Delineating the mechanisms of androgen receptor activation function-1 antagonists for development of novel prostate cancer therapeutics

Open Date: 2004-01-01

Close Date: 2021-01-01

Articles (13)

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2024

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2024

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (2)

Katherine S. Ryan

The University of British Columbia

CANADA

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Kalindi Morgan

Assistant Professor

University of Northern British Columbia

CANADA

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Marianne Sadar

Research Interests

Explore related searches

Contact this professor

Recent Grants

Articles (13)

Piperazate-Guided Isolation of Caveamides A and B, Cyclohexenylalanine-Containing Nonribosomal Peptides from a Cave Actinomycete

Treatments Targeting the Androgen Receptor and Its Splice Variants in Breast Cancer

Rational optimization of a transcription factor activation domain inhibitor

Cyclin-dependent Kinase 4/6 Inhibitor Palbociclib in Combination with Ralaniten Analogs for the Treatment of Androgen Receptor–positive Prostate and Breast Cancers

Differential Gene Expression Profiles between N-Terminal Domain and Ligand-Binding Domain Inhibitors of Androgen Receptor Reveal Ralaniten Induction of Metallothionein by a Mechanism Dependent on MTF1

Drugging the Undruggable: Targeting the N-Terminal Domain of Nuclear Hormone Receptors

Structure–Activity Relationships for the Marine Natural Product Sintokamides: Androgen Receptor N-Terminus Antagonists of Interest for Treatment of Metastatic Castration-Resistant Prostate Cancer

Pin1 inhibition improves the efficacy of ralaniten compounds that bind to the N-terminal domain of androgen receptor

Isolation and characterization of castration-resistant prostate cancer LNCaP95 clones

Combination therapy with androgen receptor N‐terminal domain antagonist EPI‐7170 and enzalutamide yields synergistic activity in AR‐V7‐positive prostate cancer

Ralaniten Sensitizes Enzalutamide-Resistant Prostate Cancer to Ionizing Radiation in Prostate Cancer Cells that Express Androgen Receptor Splice Variants

Incarnatapeptins A and B, Nonribosomal Peptides Discovered Using Genome Mining and 1H/15N HSQC-TOCSY

Discovery of drugs that directly target the intrinsically disordered region of the androgen receptor

Collaborators (2)

Katherine S. Ryan

Kalindi Morgan

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