Mariko Harada-Shiba

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Japan

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Development of antisense drug targeting primary chyromicronemia

Open Date: 2020-04-01

Close Date: 2022-03-01

Articles (14)

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2024

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2020

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2020

Collaborators (7)

Kunihiro Nishimura

Professor

Kobe University

JAPAN

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Robert Hegele

Professor

Western University

CANADA

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Tomas Freiberger

Masaryk University

CZECH REPUBLIC

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Yuji Hirowatari

Professer

Saitama University

JAPAN

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Asako Yamayoshi

Nagasaki University

JAPAN

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Marina Cuchel

UNITED STATES

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Kosuke Tsuda

Osaka Medical and Pharmaceutical University

JAPAN

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Mariko Harada-Shiba

Research Interests

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Recent Grants

Articles (14)

Publisher Correction: Dynamic and static control of the off-target interactions of antisense oligonucleotides using toehold chemistry

How can we improve the prognosis of patients with homozygous familial hypercholesterolemia?

Real-world safety and efficacy of lomitapide in homozygous familial hypercholesterolemia: interim report of special-use survey in Japan

2023 Update on European Atherosclerosis Society Consensus Statement on Homozygous Familial Hypercholesterolaemia: new treatments and clinical guidance

Dynamic and static control of the off-target interactions of antisense oligonucleotides using toehold chemistry

Current concept and residual issues of lipoprotein(a) determination for a cardiovascular risk factor

Circulating Mature PCSK9 Level Predicts Diminished Response to Statin Therapy

A Resuscitated Case of Acute Myocardial Infarction with both Familial Hypercholesterolemia Phenotype Caused by Possibly Oligogenic Variants of the PCSK9 and ABCG5 Genes and Type I CD36 Deficiency.

Lipid Management and 2-Year Clinical Outcomes in Japanese Patients with Acute Coronary Syndrome: EXPLORE-J.

Patients With <i>LDLR</i> and <i>PCSK9</i> Gene Variants Experienced Higher Incidence of Cardiovascular Outcomes in Heterozygous Familial Hypercholesterolemia.

Patients With LDLR and PCSK9 Gene Variants Experienced Higher Incidence of Cardiovascular Outcomes in Heterozygous Familial Hypercholesterolemia

A randomized study investigating the safety, tolerability, and pharmacokinetics of evinacumab, an ANGPTL3 inhibitor, in healthy Japanese and Caucasian subjects.

Guidelines on the Clinical Evaluation of Medicinal Products for Treatment of Dyslipidemia.

Artificial switching of the metabolic processing pathway of an etiologic factor, β2-microglobulin, by a "navigator" molecule.

Collaborators (7)

Kunihiro Nishimura

Robert Hegele

Tomas Freiberger

Yuji Hirowatari

Asako Yamayoshi

Marina Cuchel

Kosuke Tsuda

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