Mario Escobar

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Assistant Research Professor

Rice University

United States

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Mario Escobar is an Assistant Research Professor at Rice University in the United States. His research focuses on advanced methodologies in genome editing and transcriptional control, particularly utilizing CRISPR/Cas9 technologies. Recent publications examine the mechanistic roles of engineered transcriptional modules, biomolecular condensation, and epigenetic regulation in various cell types.

Recent Grants

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Targeted Transcriptional Gene Regulation Using Programmable Epigenetic Editors For In Vitro Cardiomyocyte Regeneration

Open Date: 2022-07-01

Close Date: 2023-05-06

Articles (6)

Year:

2025

Year:

2025

Year:

2023

Year:

2022

Year:

2022

Year:

2021

Collaborators (1)

Isaac Hilton

Associate Professor of Bioengineering

Rice University

UNITED STATES

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Mario Escobar

Research Interests

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About

Recent Grants

Articles (6)

Characterization of Rationally Designed CRISPR/Cas9-Based DNA Methyltransferases with Distinct Methyltransferase and Gene Silencing Activities in Human Cell Lines and Primary Human T Cells

Biomolecular condensation of human IDRs initiates endogenous transcription via intrachromosomal looping or high-density promoter localization

Compact engineered human mechanosensitive transactivation modules enable potent and versatile synthetic transcriptional control.

Multiplex Base-Editing Enables Combinatorial Epigenetic Regulation for Genome Mining of Fungal Natural Products.

Quantification of Genome Editing and Transcriptional Control Capabilities Reveals Hierarchies among Diverse CRISPR/Cas Systems in Human Cells

Programmable human histone phosphorylation and gene activation using a CRISPR/Cas9-based chromatin kinase

Collaborators (1)

Isaac Hilton

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